94206-80-1Relevant academic research and scientific papers
TBHP/Cu(OAc)2 mediated oxidation of pyrazolines: A convenient method for the preparation of pyrazoles
Kolla, Sai Teja,Somanaboina, Ramya,Bhimapaka, China Raju
supporting information, p. 1425 - 1432 (2021/02/27)
An efficient and simple oxidative protocol has been developed for the preparation of pyrazoles from pyrazolines mediated by TBHP/Cu(OAc)2 at room temperature. The present protocol has been successfully applied for the preparation of various pyrazole compounds from heterocyclic pyrazolines.
Copper-mediated tandem ring-opening/cyclization reactions of cyclopropanols with aryldiazonium salts: Synthesis of: N -arylpyrazoles
Liu, Jidan,Xu, Erjie,Jiang, Jinyuan,Huang, Zeng,Zheng, Liyao,Liu, Zhao-Qing
, p. 2202 - 2205 (2020/02/26)
A general method for the synthesis of structurally diverse N-arylpyrazoles from readily available cyclopropanols and aryldiazonium salts is disclosed. The reaction was conducted at room temperature within minutes with a broad substrate scope and excellent regioselectivity.
Oxone-mediated facile access to substituted pyrazoles
Kashiwa, Mitsuhiro,Kuwata, Yoshiyuki,Sonoda, Motohiro,Tanimori, Shinji
, p. 304 - 311 (2015/12/30)
An Oxone-mediated transition-metal-free oxidative C-N bond formation has been achieved for the regioselective synthesis of substituted pyrazoles. The reactions accompany the chelation-controlled ortho-oxidation of N-substituted aromatic ring to provide ph
Synthesis of Functionalized Pyrazoles via Vanadium-Catalyzed C-N Dehydrogenative Cross-Coupling and Fluorescence Switch-On Sensing of BSA Protein
Sar, Dinabandhu,Bag, Raghunath,Yashmeen, Afsana,Bag, Subhendu Sekhar,Punniyamurthy, Tharmalingam
supporting information, p. 5308 - 5311 (2015/11/18)
Vanadium-catalyzed C-N dehydrogenative cross-coupling of alkenyl hydrazones leading to functionalized pyrazoles is described in a 1:1 mixture of toluene/H2O using air as the terminal oxidant. Significant practical features include use of the commercial nontoxic VOSO4 as a recyclable catalyst, mild reaction conditions, scalability, and the broad substrate scope. Some of the product pyrazoles exhibit interesting photophysical properties. Fluorescence light-up sensing of BSA protein by one of the pyrazoles is also highlighted.
Iron-catalyzed aerobic oxidative aromatization of 1,3,5-trisubstituted pyrazolines
Ananthnag, Guddekoppa S.,Adhikari, Adithya,Balakrishna, Maravanji S.
, p. 240 - 243 (2013/12/04)
A simple and high yielding method for the synthesis of tri-substituted pyrazoles via iron(III) catalyzed aerobic oxidative aromatization of pyrazolines has been reported. The process demonstrates a variety of functional group tolerance.
