94242-54-3Relevant academic research and scientific papers
Furan-2-carbaldehydes as C1 building blocks for the synthesis of quinazolin-4(3: H)-ones via ligand-free photocatalytic C-C bond cleavage
Yu, Wenjia,Zhang, Xianwei,Qin, Bingjie,Wang, Qiyang,Ren, Xuhong,He, Xinhua
, p. 2449 - 2454 (2018/06/11)
Furan-2-carbaldehydes, as biomass-derived chemicals, are used as efficient green C1 building blocks to synthesize bioactive quinazolin-4(3H)-ones by ligand-free photocatalytic C-C bond cleavage. Notably, protection of hydroxyl, carboxyl, amide, or secondary amino groups is not required. Mechanistic studies suggest that conjugated N,O-tridentate copper complexes act as novel photoinitiators under visible light.
Ammonium chloride-catalyzed one-pot synthesis of 4(3H)-quinazolinones under solvent-free conditions
Huang, Guoli,Liu, Bo,Teng, Mingyu,Chen, Yegao
supporting information, p. 1786 - 1794 (2014/06/09)
Ammonium chloride, which is a very inexpensive and readily available reagent, can efficiently catalyze three-component, one-pot condensation reactions of 2-amino-benzoic acid esters, ortho esters, and aromatic amines to afford the corresponding 4(3H)-quinazolinones in good to excellent yields under solvent-free conditions.
Aluminium nitrate-catalyzed one-pot synthesis of 4(3h)-quinazolinones by a three-component coupling of anthranilic acid, amines, and ortho esters
Wang, Min,Song, Zhiguo,Zhang, Tingting
experimental part, p. 385 - 391 (2011/04/15)
The one-pot synthesis of quinazolinone derivatives from the reaction of anthranilic acid, amines, and ortho esters in the presence of aluminium nitrate has been carried out. The reaction occurred in a few minutes at room temperature under solvent-free con
Strontium chloride-catalyzed one-pot synthesis of 4(3H)-quinazolinones under solvent-free conditions
Wang, Min,Song, Zhi Guo,Zhang, Ting Ting
experimental part, p. 1167 - 1170 (2011/10/12)
Strontium chloride was used as an efficient and recyclable catalyst in one-pot condensation of anthranilic acid, ortho esters and amines leading to the formation of 4(3. H)-quinazolinone derivatives in good yields at room temperature under solvent-free co
Synthesis of 3-Aryl-4(3H)-quinazolinones from anthranilic acid, ortho esters, and anilines using Ce(CH3SO3)3· 2H2O as catalyst
Wang, Min,Song, Zhi-Guo,Zhang, Ting-Ting
experimental part, p. 993 - 996 (2011/10/02)
3-Aryl-4(3H)-quinazolinones were synthesized efficiently by the three component one-pot cyclocondensation of anthranilic acid, ortho esters, and anilines in the presence of Ce(CH3SO3)3·2H 2O at room temperature under solve
SnCl2·2H2O-catalyzed one-pot synthesis of 4(3H)-quinazolinones from anthranilic acid, ortho esters, and amines under solvent free conditions
Wang, Min,Song, Zhiguo,Zhang, Tingting
experimental part, p. 468 - 471 (2010/06/19)
(Chemical Equation Presented) A simple, efficient, and green procedure for the one-pot synthesis of 4(3H)-quinazolinones by three components condensation of anthranilic acid, ortho esters, and amines in the presence of SnCl 2·2H2O ha
Efficient solid phase synthesis of diverse quinazolinones
Makino,Suzuki,Nakanishi,Tsuji
, p. 1670 - 1672 (2007/10/03)
Various quinazolinones were synthesized by cyclocondensation of anthranilamides with a variety of orthoformates on solid supports. Alkyl, aryl and alkoxy groups can substitute at 2 position of quinazolines with this method. The reactions proceeded smoothly under mild acidic conditions and the products exhibited excellent purity. Unlike previously reported solid phase quinazolinone syntheses, this synthetic strategy does not require an oxidation step. The approach is applicable to the synthesis of a wide range of quinazolinones, including molecules that are susceptible to oxidation.
