942613-38-9

Basic information

• Product Name: 2-{2-[4-(4,5-dihydro-1H-imidazol-2-yl)phenyl]-ethyl}-isoindole-1,3-dione
• Synonyms: 2-{2-[4-(4,5-dihydro-1H-imidazol-2-yl)phenyl]-ethyl}-isoindole-1,3-dione
• CAS NO: 942613-38-9
• Molecular Weight: 319.363
• Mol File: 942613-38-9.mol

Chemical Properties

• CAS DataBase Reference: 2-{2-[4-(4,5-dihydro-1H-imidazol-2-yl)phenyl]-ethyl}-isoindole-1,3-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 2-{2-[4-(4,5-dihydro-1H-imidazol-2-yl)phenyl]-ethyl}-isoindole-1,3-dione(942613-38-9)
• EPA Substance Registry System: 2-{2-[4-(4,5-dihydro-1H-imidazol-2-yl)phenyl]-ethyl}-isoindole-1,3-dione(942613-38-9)

Safety Data

• Hazardous Substances Data: 942613-38-9(Hazardous Substances Data)

Upstream product

• 69395-13-7 4-(2-hydroxyethyl)benzonitrile 
• 524743-24-6 ethyl 4-(2-phthalimidoethyl)benzoate 
• 107-15-3 ethylenediamine 
• 308846-03-9 4-[2-(1,3-dioxoisoindolin-2-yl)ethyl]benzonitrile 
• 136918-14-4 phthalimide 

Downstream Products

• 1374416-64-4 C₃₅H₃₆N₄O₃S 
• 1374416-55-3 C₂₈H₂₈Cl₂N₄O₃S 
• 1374416-56-4 C₂₈H₂₈Cl₂N₄O₃S 
• 1374416-57-5 C₂₈H₂₈Cl₂N₄O₃S 
• 714568-34-0 2-[4-(4,5-dihydro-1H-imidazol-2-yl)-phenyl]-ethylamine 

Relevant articles and documents

Quinolinyl- and phenantridinyl-acetamides as bradykinin B1 receptor antagonists

A new series of quinolinyl- and phenantridinyl-acetamides were synthesizer and evaluated against bradykinin B1 receptor. In vitro metabolic stability data were reported for the key compounds.The analgesic effect of compound 20 from the phenantridine series was proved in-vivo.

NEW SULFONAMIDE DERIVATIVES AS BRADYKININ ANTAGONISTS

The present invention relates to new sulfonamide derivatives of formula (I), wherein R1 -R5 and Z are as defined in the claims, and optical antipodes or racemates and/or salts and/or hydrates and/or solvates thereof, which are selective antagonists of bradykinin B1, to processes for producing these compounds, pharmacological compositions containing them and to their use in therapy or prevention of painful and inflammatory conditions.

NEW PHENANTHRIDINE DERIVATIVES AS BRADYKININ ANTAGONISTS

The present invention relates to new phenanthridine derivatives of formula (I) wherein R1 is hydrogen atom or C1-C4 alkyl group; R2 is selected from (1) hydrogen atom; with the proviso that R1 and Rs