94265-88-0Relevant academic research and scientific papers
A synthesis of diketones from carbonyl compounds and α,ω-dichloro-α,ω-disulfinylalkanes with two carbon-carbon bond-formation via bis-sulfinyloxiranes
Satoh, Tsuyoshi,Taguchi, Daisaku,Kurabayashi, Aki,Kanoto, Makiko
, p. 4217 - 4224 (2002)
Bis-sulfinyloxiranes were synthesized in two steps from carbonyl compounds and α,ω-dichloro-α,ω-disulfinylalkanes, which were synthesized from α,ω-dibromoalkanes in three steps, in good yields. Treatment of the bis-sulfinyloxiranes with sodium benzenethiolate and piperidine gave α,α′-di(phenylthio) diketones and α,α′-diamino diketones, respectively, in high yields. From these products, some kinds of diketones were synthesized in good to high yields.
INNOVATIVE APPROACH TO THE SYNTHESIS OF SULPHIDES AND THEIR CORRESPONDING SULPHONES
Abd-El-Aziz, Alaa S.,Epp, Karen M.,Lei, Yun,Kotowich, Steven
, p. 1252 - 1286 (2007/10/02)
A general and efficient synthetic approach to aryl-aryl bis-sulphides with aliphatic or aromatic bridges via the nucleophilic aromatic substitution (SNAr) of cyclopentadienyliron arene complexes with a number of dithiols followed by photolytic demetallation is presented in this work.The oxidation of the bis(cyclopentadienyliron) arene complexes containing bis-sulphide linkages with 3-chlorobenzoic acid gave their corresponding sulphones in very good yield (70-95percent).Mixed ether/sulphide and ether/sulphone complexes were also prepared following the same synthetic strategy.Reactions of sulphide and sulphone diiron complexes with terminal chloro groups with a number of oxygen, sulphur and carbon nucleophiles allowed for the functionalization of these complexes.The use of photolytic demetallation as a means of liberating the modified arene ligands proved to be very successful.The mild conditions, high yields and low cost of the starting iron complexes make this method one of the most general and practical routes to sulphide and sulphone compounds.
