94271-74-6

Upstream product

• 105995-50-4 magnesium 4-nitrobenzyl malonate 
• 91921-98-1 [1-(2,4-dimethoxy-benzyl)-4-oxo-2-azetidinyl]-acetic acid 
• 91921-97-0 (4RS)-4-diazoacetyl-1-(2,4-dimethoxybenzyl)azetidin-2-one 
• 91921-99-2 1-(2,4-dimethoxybenzyl)-4-oxoazetidine-2-carboxylic acid 

Downstream Products

• 81946-80-7 p-nitrobenzyl (3RS,5RS)-2-oxocarbapenam-3-carboxylate 
• 81946-79-4 4-[3-(p-nitrobenzyloxycarbonyl)-3-diazo-2-oxopropyl]-azetidin-2-one 
• 94271-73-5 2-Diazo-4-[1-(2,4-dimethoxy-benzyl)-4-oxo-azetidin-2-yl]-3-oxo-butyric acid 4-nitro-benzyl ester 

Relevant academic research and scientific papers

Simple and Condensed β-Lactams. Part 5. The Synthesis of some (5RS,6SR)-2-(Formylaminoethylthio)-6-(2-methyl-1,3-dioxolan-2-yl)carbapenem-3-carboxylic Acid Derivatives and Related Compounds

Starting with the 4-oxoazetidine-2-carboxylic acids (3a) and (3b), methods for the synthesis of derivatives of the racemic carbapenem-3-carboxylic acid (2), an analogue of the potent antibiotic thienamycin have been developed.The synthetic steps included