94326-96-2Relevant academic research and scientific papers
Erbium(III) triflate: A valuable catalyst for the synthesis of aldimines, ketimines, and enaminones
Dalpozzo, Renato,De Nino, Antonio,Nardi, Monica,Russo, Beatrice,Procopio, Antonio
, p. 1127 - 1132 (2006)
Aldimines, ketimines, and enaminones can be obtained under erbium(III) inflate catalysis. The reaction mechanism is that typical of imine synthesis. The role of the catalyst is demonstrated for the synthesis of aromatic imines. In contrast to CeCl3/NaI addition to unsaturated aldehydes, which results in Michael addition, no Michael adduct was observed under erbium(III) triflate catalysis. Georg Thieme Verlag Stuttgart.
Iron-Catalyzed Mild and Selective Hydrogenative Cross-Coupling of Nitriles and Amines To Form Secondary Aldimines
Chakraborty, Subrata,Leitus, Gregory,Milstein, David
supporting information, p. 2074 - 2078 (2017/02/15)
The first example of a base-metal-catalyzed homogeneous hydrogenative coupling of nitriles and amines to selectively form secondary cross-imines is reported. The reaction is catalyzed under mild conditions by a well-defined (iPr-PNP)Fe(H)Br(CO) pincer pre-catalyst and catalytic tBuOK.
Efficient tandem synthesis of methyl esters and imines by using versatile hydrotalcite-supported gold nanoparticles
Liu, Peng,Li, Can,Hensen, Emiel J. M.
, p. 12122 - 12129 (2012/10/29)
Efficient basic hydrotalcite (HT)-supported gold nanoparticle (AuNP) catalysts have been developed for the aerobic oxidative tandem synthesis of methyl esters and imines from primary alcohols catalyzed under mild and soluble-base-free conditions. The catalytic performance can be fine-tuned for these cascade reactions by simple adjustment of the Mg/Al atomic ratio of the HT support. The one-pot synthesis of methyl esters benefits from high basicity (Mg/Al=5), whereas moderate basicity greatly improves imine selectivity (Mg/Al=2). These catalysts outperform previously reported AuNP catalysts by far. Kinetic studies show a cooperative enhancement between AuNP and the surface basic sites, which not only benefits the oxidation of the starting alcohol but also the subsequent steps of the tandem reactions. To the best of our knowledge, this is the first time that straightforward control of the composition of the support has been shown to yield optimum AuNP catalysts for different tandem reactions. Copyright
Formation of imines by selective gold-catalysed aerobic oxidative coupling of alcohols and amines under ambient conditions
Kegnaes, Soren,Mielby, Jerrik,Mentzel, Uffe V.,Christensen, Claus H.,Riisager, Anders
experimental part, p. 1437 - 1441 (2010/09/16)
The formation of imines by aerobic oxidative coupling of mixtures of alcohols and amines was studied using gold nanoparticles supported on titanium dioxide, TiO2, as a heterogeneous catalyst. The reactions were performed at ambient conditions (room temperature and atmospheric pressure) and occurred with excellent selectivity (above 98%) at moderate conversion under optimized conditions. The effect of catalytic amounts of different bases was studied, along with reaction temperature and time. Utilisation of a selective catalyst system that uses dioxygen as an oxidant and only produces water as by-product represents a new green reaction protocol for imine formation.
