94360-59-5

Basic information

• Product Name: 1,1-Cyclopropanedicarbonitrile, 2-benzoyl-3-(4-methoxyphenyl)-
• CAS NO: 94360-59-5
• Molecular Formula: C19H14N2O2
• Molecular Weight: 302.332
• Mol File: 94360-59-5.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 1,1-Cyclopropanedicarbonitrile, 2-benzoyl-3-(4-methoxyphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,1-Cyclopropanedicarbonitrile, 2-benzoyl-3-(4-methoxyphenyl)-(94360-59-5)
• EPA Substance Registry System: 1,1-Cyclopropanedicarbonitrile, 2-benzoyl-3-(4-methoxyphenyl)-(94360-59-5)

Safety Data

• Hazardous Substances Data: 94360-59-5(Hazardous Substances Data)

Upstream product

• 94360-16-4 2-Bromo-2-[1-(4-methoxy-phenyl)-3-oxo-3-phenyl-propyl]-malononitrile 
• 1885-22-9 bromomalononitrile 
• 959-33-1 3-(4-methoxyphenyl)-1-phenylprop-2-en-1-one 
• 123-11-5 4-methoxy-benzaldehyde 
• 19158-66-8 1-(2-oxo-2-phenylethyl)tetrahydrothiophenium bromide 
• 109-77-3 malononitrile 
• 109012-86-4 3-(4-methoxyphenyl)-2-cyano-5-phenyl-5-oxo-pentano-nitrile 
• 2648-61-5 2,2-dichloroacetophenone 
• 2826-26-8 2-(4-methoxyphenylmethylene)malononitrile 
• 5399-30-4 2-oxo-2-phenylethylthiocyanate 
• 16883-69-5 N-phenacylpyridinium bromide 
• 70-11-1 α-bromoacetophenone 
• 63374-35-6 3-chloro-1-(2-oxo-2-phenylethyl)pyridin-1-ium bromide 

Relevant articles and documents

A Convenient One-Pot Synthesis of Substituted 1,1-Dicyanocyclopropanes from Sulfonium Salts, Malononitrile, and Carbonyl Compounds

The three-component reaction of sulfonium salts 1, malononitrile 3, and aldehydes 2 in the ionic liquid 1-butyl-3-methylimidazolium hexafluorophosphate ([BMIM][PF6]) or in EtOH in the presence of Et3N is a convenient one-pot method for synthesis of substituted 1,1-dicyanocyclopropanes (7 and 9). The reaction of compounds 1-3 occurs stereoselectively to form substituted transcyclopropanes (7), whose structures were confirmed by the data of physicochemical methods, including X-ray diffraction analysis. The yield of cyclopropanes produced by the reaction in the ionic liquid is 8-21% higher than that in EtOH.

Stereoselective synthesis of functionalized cyclopropane derivatives via α-thiocyanate ketone-based three-component reaction

α-Thiocyanate ketone-based three-component reactions have been established for the stereoselective synthesis of functionalized electron-deficient trans-cyclopropanes. The multicomponent reactions were conducted by reacting readily available and inexpensiv

CYCLIZATION OF NITRILES. IX. SYNTHESES BASED ON 2-ARYL-3-AROYL-1,1-DICYANOPROPANES

2-Aryl-3-aroyl-1,1-dicyanopropanes and 2-aryl-3-aroyl-1-bromo-1,1-dicyanopropanes were synthesized from chalcones and malononitrile and were converted into 4,6-diaryl-2-bromo-3-cyanopyridines and 3-cyano-2(1H)-pyridinethiones.The 2-aryl-3-aroyl-1-bromo-1,1-dicyanopropanes proved convenient intermediates for the production of the corresponding cyclopropanes and other compounds.By their reaction with urea a new method was developed for the production of substituted 3-cyano-2(1H)-pyridinethiones.The 2-bromo-3-cyanopyridines contain a mobile bromine atom readily exchanged for the various nucleophilic residues of alcohols and amines and for iodide, and cyano and thiocyanato groups.The 3-cyano-2(1H)-pyridinethiones were used in the synthesis of 3-aminothienopyridines through the isolated 2-Z-methylthio-3-cyanopyridines.