94402-76-3Relevant academic research and scientific papers
Epoxidation of 2-Butene-1,4-diones with Hydrogen Peroxide in the Presence of a Catalytic Amount of Quaternary Ammonium Iodide
Sayama, Shinsei,Inamura, Yutaka
, p. 1993 - 1995 (1991)
The epoxidation of 1,4-disubstituted 2-butene-1,4-diones with 30percent aq.H2O2 in the presence of a catalytic amount of quaternary ammonium iodide afforded 2,3-epoxy-1,4-butanediones in high yield.
N-Heterocyclic Carbene Catalyzed Oxidative Coupling of Alkenes/ α-Bromoacetophenones with Aldehydes: A Facile Entry to α,β-Epoxy Ketones
Reddi, Rambabu N.,Prasad, Pragati K.,Sudalai, Arumugam
supporting information, p. 14150 - 14153 (2016/01/25)
A novel, N-heterocyclic carbene (NHC) catalyzed direct oxidative coupling of styrenes with aldehydes has been described for the synthesis of α,β-epoxy ketones in good yields. This unprecedented regioselective oxidative coupling employs NBS/DBU/DMSO (DBU=1,8-diazabicyclo [5.4. 0] undec-7-ene, DMSO=dimethylsulfoxide, NBS=N-bromosuccinimide) as an oxidative system at ambient conditions. Additionally, first NHC-catalyzed Darzens reaction of α-bromoketones and aldehydes under mild reaction conditions has also been described. Interestingly, mechanistic studies have revealed the preferred reactivity of NHC with alkene/α-bromoketone rather than aldehydes, thus proceeding via the ketodeoxy Breslow intermediate.
Remarkable effect of tris(4-fluorophenyl)phosphine oxide on the stabilization of chiral lanthanum complex catalysts. A new and practical protocol for the highly enantioselective epoxidation of conjugated enones
Kino, Rie,Daikai, Kazuhiro,Kawanami, Toshio,Fumno, Hiroshi,Inanaga, Junji
, p. 1822 - 1824 (2007/10/03)
A new and efficient chiral catalyst system, lanthanumchiral BINOL-tris(4-fluorophenyl)phosphine oxidecumene hydroperoxide, was developed for the epoxidation of α,β-unsaturated ketones thus providing the corresponding epoxy ketones with excellent enantiose
