91497-49-3

Upstream product

• 614-20-0 3-oxo-3-phenylpropionic acid 
• 64805-08-9 ethyl glyoxylate hydrate 
• 98-86-2 acetophenone 
• 6296-54-4 ethyl 2,4-dioxo-4-phenylbutyrate 
• 924-44-7 glyoxylic acid ethyl ester 
• 13735-81-4 1-styrenyloxytrimethylsilane 
• 94402-76-3 Ethyl trans-2,3-Epoxy-4-oxo-4-phenylbutanoate 
• 49653-17-0 ethyl 2-ethoxyglycolate 

Downstream Products

• 146912-63-2 (S)-2-hydroxy-4-oxo-4-phenylbutanoic acid 
• 244277-48-3 ethyl (R)-(-)-2-hydroxy-4-oxo-4-phenylbutanoate 
• 15121-89-8 ethyl 3-benzoyl acrylate 

Relevant academic research and scientific papers

Hydrogenation of ethyl esters of 4-phenyl- and (2-furyl)-substituted 2,4-dioxobutyric acids at palladium black

The hydrogenation of ethyl 4-R-2,4-dioxobutyrates (R = phenyl, 2-furyl) at 5% Pt/Al2O3 catalyst, modified with cinchonidine, and at palladium black was investigated. The former had low activity under the conditions we tested. The mai

Base- and metal-free decarboxylative aldol reaction of β-ketoacids with glyoxylate hydrates and glyoxal monohydrates in water

An environmentally benign decarboxylative aldol reaction of β-ketoacids with glyoxylate and glyoxal monohydrates in water is reported. The reaction proceeds smoothly without any base and metal catalysts, affording the corresponding β-hydroxy ketones in high yields. A preliminary mechanism study of this aldol transformation suggests a stepwise process involving the nucleophilic addition of β-ketoacids to glyoxylate hydrates and glyoxal monohydrates followed by a subsequent decarboxylation reaction.

Bismuth triflate catalyzed Mukaiyama aldol reaction in an ionic liquid

We have developed an efficient, bismuth triflate catalyzed Mukaiyama aldol reaction. The reaction proceeds rapidly and affords the corresponding β-hydroxy carbonyl compound in moderate to very good yields (up to 92%). Wiley-VCH Verlag GmbH & Co. KGaA, 200

Reductive ring-opening reaction of 2,3-epoxy-1,4-butanediones with SbCl3-Bu4NI in the presence of Na2S 2O3·5H2O

1,4-Disubstituted 2,3-epoxy-1,4-butanediones were converted to 1,4-disubstituted 2-hydroxy-1,4-butanediones with SbCl3-Bu 4NI in the presence of Na2S2O 3-5H2O. The ring opening of terminal epoxides can also be accomplished to afford the corresponding haloalcohol with SbCl3 and tetrabutylammonium halides, Bu4NX (X = Cl, Br, I) under the same reaction conditions. Copyright Taylor & Francis, Inc.