944544-10-9

Basic information

• Product Name: (2R,3R,4R,5S)-2-(benzyloxymethyl)-5-(4-benzyloxyphenyl)-3,4-dibenzyloxy-pyrrolidine
• Synonyms: (2R,3R,4R,5S)-2-(benzyloxymethyl)-5-(4-benzyloxyphenyl)-3,4-dibenzyloxy-pyrrolidine
• CAS NO: 944544-10-9
• Molecular Weight: 585.743
• Mol File: 944544-10-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2R,3R,4R,5S)-2-(benzyloxymethyl)-5-(4-benzyloxyphenyl)-3,4-dibenzyloxy-pyrrolidine(CAS DataBase Reference)
• NIST Chemistry Reference: (2R,3R,4R,5S)-2-(benzyloxymethyl)-5-(4-benzyloxyphenyl)-3,4-dibenzyloxy-pyrrolidine(944544-10-9)
• EPA Substance Registry System: (2R,3R,4R,5S)-2-(benzyloxymethyl)-5-(4-benzyloxyphenyl)-3,4-dibenzyloxy-pyrrolidine(944544-10-9)

Safety Data

• Hazardous Substances Data: 944544-10-9(Hazardous Substances Data)

Upstream product

• 944544-00-7 (3S,4R,5R)-5-benzyloxymethyl-1-(tert-butoxycarbonyl)-3,4-dibenzyloxy-pyrrolidin-2-one 
• 120186-59-6 (4-(benzyloxy)phenyl)magnesium bromide 
• 116679-01-7 L-O,O-dibenzyltartaric acid 
• 158349-27-0 (3S,4R,5R)-3,4-bis(benzyloxy)-5-(benzyloxymethyl)pyrrolidin-2-one 
• 113321-58-7 (2S,3S)-diethyl 2,3-bis(phenylmethoxy)succinate 
• 3587-60-8 Benzyloxymethyl chloride 
• 944543-97-9 C₃₄H₃₅NO₆ 
• 944543-96-8 (3S,4S)-1-(4-methoxybenzyl)-3,4-dibenzyloxy-2,5-pyrrolidinedione 
• 944543-93-5 (3S,4R,5R)-5-benzyloxymethyl-3,4-dibenzyloxy-1-(4-methoxybenzyl)-pyrrolidin-2-one 

Downstream Products

• 188744-98-1 (2R,3R,4R,5S)-2-(hydroxymethyl)-5-(4-hydroxyphenyl)pyrrolidine-3,4-diol 

Relevant articles and documents

A versatile approach to pyrrolidine azasugars and homoazasugars based on a highly diastereoselective reductive benzyloxymethylation of protected tartarimide

A highly diastereoselective synthesis of enantio-enriched all trans-3,4-dibenzyloxyl-5-benzyloxymethyl-2-pyrrolidinone 13a was developed based on SmI2-mediated benzyloxymethylation of O,O′-dibenzyltartarimide. The versatility of 13a and its antipode as the key building blocks for the asymmetric synthesis of pyrrolidine azasugars and homoazasugars has been demonstrated by elaborating them into naturally occurring DAB 1 (1), LAB 1 (2), N-hydroxyethyl-DAB 1 (4), 6-deoxy-DMDP 7, and 5-epi-radicamine B 36 as well as the reductive ring-opening product 35.