944719-58-8

Basic information

• Product Name: 2-(4-bromophenyl)benzo[d][1,2]selenazol-3(2H)-one
• Synonyms: 2-(4-bromophenyl)benzo[d][1,2]selenazol-3(2H)-one
• CAS NO: 944719-58-8
• Molecular Weight: 353.077
• Mol File: 944719-58-8.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 2-(4-bromophenyl)benzo[d][1,2]selenazol-3(2H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-bromophenyl)benzo[d][1,2]selenazol-3(2H)-one(944719-58-8)
• EPA Substance Registry System: 2-(4-bromophenyl)benzo[d][1,2]selenazol-3(2H)-one(944719-58-8)

Safety Data

• Hazardous Substances Data: 944719-58-8(Hazardous Substances Data)

Upstream product

• 609-67-6 2-Iodobenzoyl chloride 
• 106-40-1 4-bromo-aniline 
• 6512-83-0 2,2'-diselanediyl-di-benzoic acid 
• 313268-47-2 2-iodo N-(4-bromophenyl)benzamide 
• 118-92-3 anthranilic acid 
• 1441-85-6 2-(chloroseleno)benzoyl chloride 

Downstream Products

• 1319258-24-6 2,2'-diselenobis[N-(4-bromophenyl)benzamide] 

Relevant articles and documents

A simple and efficient fluorescent probe for rapidly detecting H2S in GBC - SD cells based on 1,8 - naphthalimide - ebselen

A novel 1,8 - naphthalimide - ebselen fluorescent probe BPHN was synthesized. BPHN has great fluorescence properties: high quantum yield (0.5932), large Stokes shift (125 nm) and remarkable stability at wide pH range (5–11). The results of fluorescence sp

Water-dependent synthesis of biologically active diaryl diselenides

A new one-step method for the synthesis of diaryl diselenides has been developed. The reaction of o-iodobenzamides with dilithium diselenide can be controlled by the presence of water providing a simple and efficient protocol to obtain benzisoselenazolones or diaryl diselenides. A series of N-Aryl ebselen derivatives and the corresponding diselenides was obtained. All synthesized compounds were tested in vitro as antioxidants and cytotoxic agents. N-(2,3,4-Trimethoxyphenyl)benzisoselenazol-3(2H)-one was the best in vitro antioxidant and the corresponding diselenide the most potent cytotoxic agent against prostate cancer cell line DU145, being inactive towards healthy prostate cell line PNT1A. Formula parented.

Cu-catalyzed efficient synthetic methodology for ebselen and related se-N heterocycles

An efficient copper-catalyzed method for the synthesis of biologically important ebselen and related analogues containing a Se-N bond has been developed. This is the first report of a catalytic process of selenation and Se-N bond formation reaction. Copper-catalyzed reaction tolerates functional groups such as amides, hydroxyls, ethers, nitro, fluorides, and chlorides. The best results are obtained by using a combination of potassium carbonate as a base, iodo- or bromo-arylamide substrates, selenium powder, and copper iodide catalyst.