944732-36-9Relevant academic research and scientific papers
Multivalent polyglycerol supported imidazolidin-4-one organocatalysts for enantioselective Friedel-Crafts alkylations
Pecchioli, Tommaso,Muthyala, Manoj Kumar,Haag, Rainer,Christmann, Mathias
, p. 730 - 738 (2015/06/08)
The first immobilization of a MacMillan's first generation organocatalyst onto dendritic support is described. A modified tyrosine-based imidazolidin-4-one was grafted to a soluble high-loading hyperbranched polyglycerol via a copper-catalyzed alkyne-azide cycloaddition (CuAAC) reaction and readily purified by dialysis. The efficiency of differently functionalized multivalent organocatalysts 4a-c was tested in the asymmetric Friedel-Crafts alkylation of N-methylpyrrole with α,β-unsaturated aldehydes. A variety of substituted enals was investigated to explore the activity of the catalytic system which was also compared with monovalent analogues. The catalyst 4b showed excellent turnover rates and no loss of activity due to immobilization, albeit moderate enantioselectivities were observed. Moreover, easy recovery by selective precipitation allowed the reuse of the catalyst for three cycles.
Recyclable tetraarylphosphonium supported chiral imidazolidin-4-one organocatalyst for Diels-Alder reactions
Lin, Zihan,Chen, Zuxing,Yang, Guichun,Lu, Cuifen
, p. 1 - 5 (2013/05/09)
The tetraarylphosphonium supported chiral imidazolidin-4-ones were synthesized and used to catalyze the Diels-Alder reactions of cyclopentadiene and α,β-unsaturated aldehydes. High enantiomeric excesses and good yields were obtained, and catalyst recyclin
HETEROGENEOUS CHIRAL CATALYST
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Page/Page column 12, (2009/12/04)
The invention provides a heterogeneous catalyst comprising a catalytic group coupled to a mesocellular siliceous foam support. The catalytic group is capable of catalysing a reaction selected from the group consisting of a Friedel-Craft reaction and a Die
Enantioselective catalysis over chiral imidazolidin-4-one immobilized on siliceous and polymer-coated mesocellular foams
Zhang, Yugen,Zhao, Lan,Lee, Su Seong,Ying, Jackie Y.
, p. 2027 - 2032 (2007/10/03)
A highly efficient and enantioselective organocatalyst, imidazolidin-4-one, has been successfully immobilized on siliceous MCF and polymer-coated MCF. The resulting heterogenized catalyst demonstrated excellent catalytic performance and recyclability for
