945523-52-4

Basic information

• Product Name: 1-(cyclohexylethynyl)-2-nitrobenzene
• Synonyms: 1-(cyclohexylethynyl)-2-nitrobenzene
• CAS NO: 945523-52-4
• Molecular Weight: 229.279
• Mol File: 945523-52-4.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 1-(cyclohexylethynyl)-2-nitrobenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(cyclohexylethynyl)-2-nitrobenzene(945523-52-4)
• EPA Substance Registry System: 1-(cyclohexylethynyl)-2-nitrobenzene(945523-52-4)

Safety Data

• Hazardous Substances Data: 945523-52-4(Hazardous Substances Data)

Upstream product

• 931-48-6 2-cyclohexylacetylene 
• 577-19-5 2-nitrophenyl bromide 
• 1493-27-2 ortho-nitrofluorobenzene 
• 609-73-4 o-nitroiodobenzene 

Downstream Products

• 13141-48-5 2-cyclohexyl-1H-indole 
• 899419-79-5 tert-butyl 2-cyclohexyl-1H-indole-1-carboxylate 
• 287477-26-3 2-(2-cyclohexylethynyl)aniline 

Relevant articles and documents

Synthesis of N-Hydroxyindole Derivatives via Pd-Catalyzed Electrophilic Cyclization

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Efficient nucleophilic aromatic substitution between aryl nitrofluorides and alkynes

Equation Presented The nucleophilic aromatic substitution reaction between electron-deficient aryl fluorides and terminal alkynes is shown to be efficiently promoted by sodium bis(trimethylsilyl)amide as a base. Moderate to excellent yields of 2-ethynylnitrobenzene products can be obtained under mild conditions.