945523-52-4Relevant academic research and scientific papers
Catalytic asymmetric formal [3+2] cycloaddition of isatogens with azlactones to construct indolin-3-one derivatives
Xie, Lihua,Li, Yi,Dong, Shunxi,Feng, Xiaoming,Liu, Xiaohua
supporting information, p. 239 - 242 (2021/01/14)
The chiral amide-guanidine-catalyzed asymmetric formal [3+2] cycloaddition of isatogens with azlactones is presented. This strategy provided a facile and feasible route to chiral indolin-3-one derivatives bearing two contiguous tetrasubstituted stereocent
Efficient nucleophilic aromatic substitution between aryl nitrofluorides and alkynes
DeRoy, Patrick L.,Surprenant, Simon,Bertrand-Laperle, Megan,Yoakim, Christiane
, p. 2741 - 2743 (2008/02/08)
Equation Presented The nucleophilic aromatic substitution reaction between electron-deficient aryl fluorides and terminal alkynes is shown to be efficiently promoted by sodium bis(trimethylsilyl)amide as a base. Moderate to excellent yields of 2-ethynylnitrobenzene products can be obtained under mild conditions.
Ruthenium-catalyzed asymmetric hydrogenation of N-Boc-indoles
Kuwano, Ryoichi,Kashiwabara, Manabu
, p. 2653 - 2655 (2007/10/03)
Highly enantioselective hydrogenation of various N-Boc-indoles proceeded successfully in the presence of the ruthenium complex generated from an appropriate ruthenium precursor and a trans-chelate chiral bisphosphine PhTRAP. Various 2- or 3-substituted indoles were converted into chiral indolines with high enantiomeric excesses (up to 95% ee). The PhTRAP-ruthenium catalyst was able to promote the hydrogenation of 2,3-dimethylindoles, giving cis-2,3-dimethylindolines with 72% ee.
