946614-48-8

Basic information

• Product Name: methyl 2-(2-(cyanomethyl)-6-methoxy-4-methylphenyl)acetonitrile
• Synonyms: methyl 2-(2-(cyanomethyl)-6-methoxy-4-methylphenyl)acetonitrile
• CAS NO: 946614-48-8
• Molecular Weight: 377.397
• Mol File: 946614-48-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: methyl 2-(2-(cyanomethyl)-6-methoxy-4-methylphenyl)acetonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 2-(2-(cyanomethyl)-6-methoxy-4-methylphenyl)acetonitrile(946614-48-8)
• EPA Substance Registry System: methyl 2-(2-(cyanomethyl)-6-methoxy-4-methylphenyl)acetonitrile(946614-48-8)

Safety Data

• Hazardous Substances Data: 946614-48-8(Hazardous Substances Data)

Upstream product

• 126712-07-0 2-bromo-6-methoxybenzaldehyde 
• 18107-18-1 diazomethyl-trimethyl-silane 
• 134111-88-9 methyl 7-methoxy-3-oxo-2,3-dihydro-1H-indene-1-carboxylate 
• 946614-58-0 7-methoxy-3-oxo-2,3-dihydro-1H-indene-1-carboxylic acid 
• 874-63-5 3,5-dimethylmethoxybenzene 
• 40731-98-4 4-hydroxy-2,3-dihydroindan-1-one 
• 13336-31-7 4-methoxylindanone 
• 946614-46-6 2-(2-iodo-3-methoxy-5-methylphenyl)acetonitrile 
• 946614-47-7 2-(3-methoxy-5-methyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)acetonitrile 
• 946614-39-7 methyl 2-bromo-7-methoxy-3H-indene-1-carboxylate 
• 119-84-6 C₆H₄(CH₂CH₂C(O)O) 
• 119650-45-2 (2-iodo-3-methoxy-5-methylphenyl)methanol 
• 119650-44-1 (3-methoxy-5-methylphenyl)methanol 

Relevant articles and documents

A gold-catalyzed cycloisomerization/aerobic oxidation cascade strategy for 2-aryl indenones from 1,5-enynes

A unique gold(i)-catalyzed 5-endo-dig cyclization/aerobic oxidation cascade strategy from 1,5-enyne substrates with molecular oxygen as the oxidant to yield the indenone was described. The reaction mechanism was studied by heavy atom labelling and some related experiments. This method was applied to the formal total synthesis of isoprekinamycin.