94709-12-3Relevant academic research and scientific papers
Highly Selective and Divergent Acyl and Aryl Cross-Couplings of Amides via Ir-Catalyzed C-H Borylation/N-C(O) Activation
Gao, Pengcheng,Szostak, Michal
supporting information, p. 6010 - 6015 (2020/07/30)
Herein, we demonstrate that amides can be readily coupled with nonactivated arenes via sequential Ir-catalyzed C-H borylation/N-C(O) activation. This methodology provides facile access to biaryl ketones and biaryls by the sterically controlled Ir-catalyzed C-H borylation and divergent acyl and decarbonylative amide N-C(O) and C-C activation. The methodology diverts the traditional acylation and arylation regioselectivity, allowing us to directly utilize readily available arenes and amides to produce valuable ketone and biaryl motifs.
Carbonylative Suzuki-Miyaura coupling catalyzed by palladium supported on aminopropyl polymethylsiloxane microspheres under atmospheric pressure of CO
Zawartka, Wojciech,Po?piech, Piotr,Cypryk, Marek,Trzeciak, Anna M.
, p. 76 - 80 (2016/04/04)
Carbonylative Suzuki-Miyaura cross-coupling reactions of various aryl iodides with phenylboronic acids were catalyzed by palladium supported on amino-modified silica microspheres. Reactions performed with a very low concentration of Pd, under the atmospheric pressure of CO, led to high/moderate yields of multiple benzophenones.
Palladium nanoparticles supported on a nickel pyrazolate metal organic framework as a catalyst for Suzuki and carbonylative Suzuki couplings
Augustyniak,Zawartka,Navarro,Trzeciak
supporting information, p. 13525 - 13531 (2016/09/04)
Methanolic reduction of [PdCl2(CH3CN)2] on a [Ni(2,5-di(1H-pyrazol-4-yl)benzenesulfonate)2] metal organic framework gives rise to Pd2+/Pd0 nanocomposites with Suzuki and carbonylative Suzuki heterogeneous catalytic activities.
Antineoplastic agents. 465. Structural modification of resveratrol: Sodium resverastatin phosphate
Pettit, George R.,Grealish, Matthew P.,Jung, M. Katherine,Hamel, Ernest,Pettit, Robin K.,Chapuis, J.-Charles,Schmidt, Jean M.
, p. 2534 - 2542 (2007/10/03)
As an extension of structure/activity investigations of resveratrol (1), phenstatin (2c), and the cancer antiangiogenesis drug sodium combretastatin A-4 phosphate (2b), syntheses of certain related stilbenes (14) and benzophenones (16) were undertaken. The trimethyl ether derivative of (Z)-resveratrol (4a) exhibited the strongest activity (GI50 = 0.01-0.001 μg/mL) against a minipanel of human cancer cell lines. A monodemethylated derivative (14c) was converted to prodrug 14n (sodium resverastatin phosphate) for further biological evaluation. The antitubulin and antimicrobial activities of selected compounds were also evaluated.
