947144-58-3

Upstream product

• 947144-56-1 2,6-dibromopyridin-4-yl-N-nitroamine 
• 848470-14-4 2,6-dibromo-3-nitropyridin-4-ylamine 
• 98027-81-7 2,6-dibromo-4-nitro-pyridine 1-oxide 
• 25373-69-7 2,6-dibromopyridin N-oxide 
• 39771-34-1 4-amino-2,6-dibromopyridine 
• 626-05-1 2,6-Dibromopyridine 
• 947144-60-7 2,6-dibromo-3-nitro-4-chloropyridine 
• 100-46-9 benzylamine 

Downstream Products

• 947144-86-7 6-Allyl-N₂,N₄-dibenzyl-3-nitro-pyridine-2,4-diamine 
• 947144-62-9 N₂,N₄-dibenzyl-3-nitro-6-vinyl-pyridine-2,4-diamine 
• 947144-70-9 1-(4,6-bis-benzylamino-5-nitro-pyridin-2-yl)-ethanone 
• 947144-84-5 N₂,N₄-dibenzyl-3-nitro-6-pyrazin-2-yl-pyridine-2,4-diamine 
• 947144-74-3 4,6-bis-benzylamino-5-nitro-pyridine-2-carbonitrile 
• 947143-81-9 N₂,N₄-Dibenzyl-6-oxazol-2-yl-pyridine-2,3,4-triamine 
• 1340588-51-3 C₂₃H₁₉N₅O₂ 
• 947145-01-9 N,N'-dibenzyl-3-nitro-6-oxazol-2-yl-pyridine-2,4-diamine 
• 947145-03-1 N₂,N₄-Dibenzyl-6-(1-methyl-1H-imidazol-2-yl)-3-nitro-pyridine-2,4-diamine 
• 947146-68-1 4,6-bis-benzylamino-5-nitro-pyridine-2-carboxylic acid methyl ester 

Relevant academic research and scientific papers

A flexible synthesis of C-6 and N-1 analogues of a 4-amino-1,3- dihydroimidazo[4,5-c]pyridin-2-one core

A flexible route which enables access to derivatives of 4-amino-1,3-dihydroimidazo[4,5-c]pyridin-2-ones is described. Issues of selectivity, reaction safety, and low yields in original routes are overcome with the key improvements to the route, including

NOVEL PHARMACEUTICALS

The present invention relates to immune response modifiers of formula (I), which act selectively through agonism, of Toll-Like Receptors (TLRs), uses thereof, processes for the preparation thereof, intermediates used in the preparation thereof and compositions containing said inhibitors. These inhibitors have utility in a variety of therapeutic areas including the treatment of infectious disease such as Hepatitis (e.g. HCV, HBV), genetically related viral infection and cancer.