848470-14-4

Basic information

• Product Name: 4-Amino-2,6-dibromo-3-nitropyridine
• Synonyms: 4-Amino-2,6-dibromo-3-nitropyridine;4-AMino-2,5-dibroMo-3-nitropyridine;4-Amino-2,6-Dibromo-3-Nitropyridine(WX609249)
• CAS NO: 848470-14-4
• Molecular Formula: C₅H₃Br₂N₃O₂
• Molecular Weight: 296.9
• Mol File: 848470-14-4.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 396.5±37.0 °C(Predicted)
• Appearance: /
• Density: 2.298±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C(protect from light)
• PKA: -3.35±0.50(Predicted)
• CAS DataBase Reference: 4-Amino-2,6-dibromo-3-nitropyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Amino-2,6-dibromo-3-nitropyridine(848470-14-4)
• EPA Substance Registry System: 4-Amino-2,6-dibromo-3-nitropyridine(848470-14-4)

Safety Data

• Hazardous Substances Data: 848470-14-4(Hazardous Substances Data)

Usage

General Description

4-Amino-2,6-dibromo-3-nitropyridine is a chemical compound with the molecular formula C5H3BrN3O2. It is a yellow to orange crystalline solid that is commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. It is also used as a building block in the production of dyes and corrosion inhibitors. 4-Amino-2,6-dibromo-3-nitropyridine is a derivative of pyridine, with two bromine atoms and a nitro group attached to the aromatic ring. Its chemical properties include its ability to undergo substitution and reduction reactions. Due to its potential for biological activity and its versatile reactivity, 4-Amino-2,6-dibromo-3-nitropyridine is widely utilized in the synthesis of various organic compounds.

Upstream product

• 98027-81-7 2,6-dibromo-4-nitro-pyridine 1-oxide 
• 25373-69-7 2,6-dibromopyridin N-oxide 
• 626-05-1 2,6-Dibromopyridine 
• 2587-03-3 2,6-dichloro-N-nitro-4-pyridinamine 
• 2587-02-2 2,6-dichloro-[4]pyridylamine 
• 947144-56-1 2,6-dibromopyridin-4-yl-N-nitroamine 
• 2897-43-0 2,6-dichloro-3-nitropyridin-4-amine 
• 39771-34-1 4-amino-2,6-dibromopyridine 

Downstream Products

• 947144-60-7 2,6-dibromo-3-nitro-4-chloropyridine 
• 1303438-97-2 N₄-benzyl-2,6-dibromopyridine-3,4-diamine 
• 1303438-98-3 1-benzyl-5,7-dibromopyrido[4,3-b]pyrazine-2,3(1H,4H)-dione 
• 1303438-99-4 5-amino-1-benzyl-7-bromopyrido[4,3-b]pyrazine-2(1H,4H)-dione 
• 1303439-12-4 tert-butyl benzyl(2,6-dibromo-3-nitropyridin-4-yl)carbamate 
• 947144-58-3 N,N'-dibenzyl-6-bromo-3-nitropyridine-2,4-diamine 
• 947145-01-9 N,N'-dibenzyl-3-nitro-6-oxazol-2-yl-pyridine-2,4-diamine 
• 947143-81-9 N₂,N₄-Dibenzyl-6-oxazol-2-yl-pyridine-2,3,4-triamine 
• 1340588-51-3 C₂₃H₁₉N₅O₂ 
• 947145-82-6 [2-amino-6-(4-methyl-oxazol-2-yl)-3-nitro-pyridin-4-yl]-(3-cyano-benzyl)-carbamic acid ethyl ester 
• 947145-74-6 (2-amino-6-bromo-3-nitro-pyridin-4-yl)-(3-cyano-benzyl)-carbamic acid ethyl ester 
• 947145-72-4 (3-cyano-benzyl)-(2,6-dibromo-3-nitro-pyridin-4-yl)-carbamic acid ethyl ester 
• 1303438-96-1 N-benzyl-2,6-dibromo-3-nitropyridin-4-amine 
• 947146-08-9 N₂,N₂-dibenzyl-6-bromo-3-nitro-pyridine-2,4-diamine 

Relevant articles and documents

Design and optimisation of orally active TLR7 agonists for the treatment of hepatitis C virus infection

The synthesis and structure-activity relationships of a series of novel interferon inducers are described. Pharmacokinetic studies and efficacy assessment of a series of 8-oxo-3-deazapurine analogues led to the identification of compound 33, a potent and selective agonist of the TLR7 receptor with an excellent in vivo efficacy profile in a mouse model.

A flexible synthesis of C-6 and N-1 analogues of a 4-amino-1,3- dihydroimidazo[4,5-c]pyridin-2-one core

A flexible route which enables access to derivatives of 4-amino-1,3-dihydroimidazo[4,5-c]pyridin-2-ones is described. Issues of selectivity, reaction safety, and low yields in original routes are overcome with the key improvements to the route, including

PHARMACOLOGICALLY ACTIVE IMIDAZO[4,5-C]PYRIDINES

The invention relates to 6-substituted imidazo[4,5-c]pyridines of formula 1, in which X is O (oxygen) or NH and Y has either the meaning -CH2-AR or Y denotes the group gp (gp) wherein Z has the meaning -CHR8- or -CHR8-CHR9-. The compounds have gastric secretion inhibiting and excellent gastric and intestinal protective action properties.