947490-12-2Relevant academic research and scientific papers
Synthesis and anti-rotavirus activity of some nitrogen heterocycles integrated with pyrazole scaffold
El-Helw, Eman A. E.,Gado, Marwa M.,El-Ziaty, Ahmed K.
, p. 1479 - 1492 (2020)
Herein, the building block synthon 2-cyano-3-(1,3-diphenyl-1H-pyrazol-4-yl)acryloyl chloride 4 was synthesized and utilized for construction of a wide variety of nitrogen heterocycles encompassing a pyrazole scaffold via treatment with some nitrogen nucle
Cytotoxic and antimicrobial activities of some novel heterocycles employing 6-(1,3-diphenyl-1H-pyrazol-4-yl)-4-oxo-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carbonitrile
Ramadan, Sayed K.,El-Helw, Eman A. E.,Sallam, Hanan A.
, p. 107 - 115 (2019)
A pyrimidinethione derivative namely, 6-(1,3-diphenyl-1H-pyrazol-4-yl)-4-oxo-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carbonitrile, was readily synthesized and reacted with carbon electrophiles in an attempt to synthesize selected fused heterocycles. The r
Synthesis and antimicrobial activity of some new 1,3-diphenylpyrazoles bearing pyrimidine, pyrimidinethione, thiazolopyrimidine, triazolopyrimidine, thio- and alkylthiotriazolopyrimidinone moieties at the 4-position
El-Emary,Abdel-Mohsen, Sh. A.
, p. 2459 - 2474 (2007/10/03)
1,3-diphenyl-1H-pyrazole-4-carboxaldehyde (1) reacted with ethyl cyanoacetate and thiourea to give the pyrimidinethione derivative 2. The reaction of 2 with some alkylating agents gave the corresponding thioethers 3a-e and 7. Thione 2 was cyclized to 5 an
