948017-82-1

Basic information

• Product Name: (R)-4-Amino-3-(4-chloro-phenyl)-butyric acid methyl ester
• Synonyms: (R)-4-Amino-3-(4-chloro-phenyl)-butyric acid methyl ester
• CAS NO: 948017-82-1
• Molecular Weight: 227.691
• Mol File: 948017-82-1.mol

Chemical Properties

• CAS DataBase Reference: (R)-4-Amino-3-(4-chloro-phenyl)-butyric acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-4-Amino-3-(4-chloro-phenyl)-butyric acid methyl ester(948017-82-1)
• EPA Substance Registry System: (R)-4-Amino-3-(4-chloro-phenyl)-butyric acid methyl ester(948017-82-1)

Safety Data

• Hazardous Substances Data: 948017-82-1(Hazardous Substances Data)

Upstream product

• 67-56-1 methanol 
• 63701-55-3 (R)-(-)-baclofen hydrochloride 
• 164527-50-8 (+)-2-[1-(4-chloro-phenyl)-allyl]-malonic acid dimethyl ester 
• 496789-08-3 1-(4'-chlorophenyl)-prop-2-enyl methyl carbonate 

Downstream Products

• 63701-55-3 (R)-(-)-baclofen hydrochloride 
• 123632-35-9 (R)-(-)-4-(4-chlorophenyl)pyrrolidin-2-one 

Relevant articles and documents

Recoverable resin-supported pyridylamide ligand for microwave-accelerated molybdenum-catalyzed asymmetric allylic alkylations: Enantioselective synthesis of baclofen

(Matrix presented) The syntheses of a series of 4-monosubstituted pyridylamides and a resin-supported pyridylamide are described. The ligands were evaluated in the microwave-accelerated molybdenum-catalyzed asymmetric allylic alkylation. The reaction affo

Enantioselective syntheses of (R)-3-phenyl GABA, (R)-baclofen and 4-arylpyrrolidin-2-ones

Enantioselective synthesis of (R)-4-amino-3-phenylbutyric acid and (R)-baclofen has been achieved through a diastereoselective conjugate addition of cyanide to enantiomerically pure 2-(2-arylethenyl)oxazolines, followed by chemoselective reduction into cyclic amidines.