164527-50-8

Basic information

• Product Name: Propanedioic acid, [(1R)-1-(4-chlorophenyl)-2-propenyl]-, dimethyl ester
• CAS NO: 164527-50-8
• Molecular Formula: C14H15ClO4
• Molecular Weight: 282.724
• Mol File: 164527-50-8.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: Propanedioic acid, [(1R)-1-(4-chlorophenyl)-2-propenyl]-, dimethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Propanedioic acid, [(1R)-1-(4-chlorophenyl)-2-propenyl]-, dimethyl ester(164527-50-8)
• EPA Substance Registry System: Propanedioic acid, [(1R)-1-(4-chlorophenyl)-2-propenyl]-, dimethyl ester(164527-50-8)

Safety Data

• Hazardous Substances Data: 164527-50-8(Hazardous Substances Data)

Upstream product

• 776296-22-1 3-(4-chlorophenyl)allyl methyl carbonate 
• 108-59-8 malonic acid dimethyl ester 
• 496789-08-3 1-(4'-chlorophenyl)-prop-2-enyl methyl carbonate 
• 170938-16-6 (E)-3-(4'-chlorophenyl)-prop-2-enyl methyl carbonate 
• 18424-76-5 dimethyl malonate sodium salt 
• 105643-16-1 (1'R,S)-1-(4-chlorophenyl)-2-propene-1-acetate 
• 170938-14-4 (E)-3-(4-chlorophenyl)allyl acetate 
• 164527-44-0 diethyl (E)-3-(4-chlorophenyl)prop-2-enyl phosphate 

Downstream Products

• 948017-82-1 (R)-4-Amino-3-(4-chloro-phenyl)-butyric acid methyl ester 
• 63701-55-3 (R)-(-)-baclofen hydrochloride 

Relevant articles and documents

Recoverable resin-supported pyridylamide ligand for microwave-accelerated molybdenum-catalyzed asymmetric allylic alkylations: Enantioselective synthesis of baclofen

(Matrix presented) The syntheses of a series of 4-monosubstituted pyridylamides and a resin-supported pyridylamide are described. The ligands were evaluated in the microwave-accelerated molybdenum-catalyzed asymmetric allylic alkylation. The reaction affo

Synthesis of 1-[bis(trifluoromethyl)phosphine]-1'- oxazolinylferrocene ligands and their application in regio- and enantioselective Pd-catalyzed allylic alkylation of monosubstituted allyl substrates

A class of novel, easily accessible and air-stable 1-[bis(trifluoromethyl) phosphine]-1'-oxazolinylferrocene ligands has been synthesized from ferrocene. It became apparent that these ligands can be used in the regio- and enantioselective Pd-catalyzed allylic alkylation of monosubstituted allyl substrates in a highly efficient manner. Excellent regio- and enantioselectivity could be obtained for a wide range of substrates.

Ir-catalyzed asymmetric allylic alkylation using chiral diaminophosphine oxides: DIAPHOXs. Formal enantioselective synthesis of (-)-paroxetine

An Ir-catalyzed asymmetric allylic alkylation using chiral diaminophosphine oxide is described. Asymmetric allylic alkylation of terminal allylic carbonates proceeded using 5 mol % of Ir catalyst, 5 mol % of DIAPHOX 1i, 10 mol % of NaPF6, 10 mo