94805-52-4

Basic information

• Product Name: 3-CYANO-6-HYDROXYPYRIDINE
• Synonyms: 2-HYDROXY-5-CYANO PYRIDINE;5-CYANO-2-HYDROXYPYRIDINE;5-CYANO-2(1H)-PYRIDINONE;3-CYANO-6-HYDROXYPYRIDINE;6-Hydroxynicotinonitrile 98%;3-Pyridinecarbonitrile,1,6-dihydro-6-oxo-(9CI);6-HYDROXYNICOTINONITRILE (3-CYANO-6-HYDROXY PYRIDINE);3-CYANO-6-HYDROXYPYRIDINE / 2-HYDROXY-5-CYANOPYRIDINE
• CAS NO: 94805-52-4
• Molecular Formula: C₆H₄N₂O
• Molecular Weight: 120.11
• EINECS: 1308068-626-2
• Product Categories: NITRILE;blocks;Carboxes;Pyridines
• Mol File: 94805-52-4.mol
• Article Data: 4

Chemical Properties

• Melting Point: 256-258
• Boiling Point: 404.847 °C at 760 mmHg
• Flash Point: 198.644 °C
• Appearance: light yellow cryst
• Density: 1.332 g/cm³
• Vapor Pressure: 0.000143mmHg at 25°C
• Refractive Index: 1.571
• Storage Temp.: Keep Cold
• PKA: 8.67±0.10(Predicted)
• CAS DataBase Reference: 3-CYANO-6-HYDROXYPYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-CYANO-6-HYDROXYPYRIDINE(94805-52-4)
• EPA Substance Registry System: 3-CYANO-6-HYDROXYPYRIDINE(94805-52-4)

Safety Data

• Hazard Codes: Xi,Xn
• Statements: 36/37/38-22
• Safety Statements: 26-36
• HazardClass: IRRITANT
• Hazardous Substances Data: 94805-52-4(Hazardous Substances Data)

Usage

Chemical Properties

Light yellow Cryst

InChI:InChI=1/C6H4N2O/c7-3-5-1-2-6(9)8-4-5/h1-2,4H,(H,8,9)

Upstream product

• 33630-94-3 5-amino-2-hydroxypyridine 
• 151-50-8 potassium cyanide 
• 20511-12-0 2-amino-5-iodopyridine 
• 1072-97-5 5-bromo-2-pyridylamine 
• 100-54-9 pyridine-3-carbonitrile 
• 106853-78-5 6-ethoxy-nicotinonitrile 
• 4214-73-7 6-aminonicotinonitrile 

Downstream Products

• 320405-84-3 6-hydroxy-5-nitropyridine-3-carbonitrile 
• 160906-98-9 6-chloro-5-nitro-3-pyridinecarbonitrile 
• 906480-78-2 6-{3-[4-(5,7-dihydro-pyrrolo[3,4-b]pyridin-6-yl)-3-fluoro-phenyl]-2-oxo-oxazolidin-5-ylmethoxy}-nicotinonitrile 
• 33252-28-7 6-chloronicotinonitrile 

Relevant articles and documents

Microbial hydroxylation of 3-cyanopyridine to 3-cyano-6-hydroxypyridine

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Synthesis of a series of iridium complexes bearing substituted 2-pyridonates and their catalytic performance for acceptorless dehydrogenation of alcohols under neutral conditions

A series of Cp*Ir complexes bearing 5- and 4,5-substituted 2-pyridonate ligands have been synthesized and their catalytic performance for acceptorless dehydrogenation of alcohols has been investigated under neutral conditions. Electron-withdrawing groups such as methoxycarbonyl, trifluoromethyl, cyano, and nitro groups at the 5-position promoted the acceptorless dehydrogenation of 1-phenylethanol, whereas electron-donating methyl group at the 5-position retarded the reaction. Furthermore, introduction of methyl group at the 4-position improved the catalytic performance. Thus, Cp*Ir(5-trifluoromethyl-4-methyl-2-pyridonate)Cl (2bc) exhibited the highest catalytic performance among the complexes examined, and also showed good catalytic performance for acceptorless dehydrogenation of primary alcohols.