94833-28-0

Upstream product

• 35248-33-0 2-piperidino-1-benzoyl-1-cyclohexene 
• 7357-70-2 Cyanothioacetamide 
• 6944-34-9 dithiomalonamide 
• 5292-56-8 2-benzoyl-1-(morpholin-4-yl)-1-cyclohexene 
• 129224-53-9 2-cyano-2-cyclohexylidenethioacetamide 
• 100-52-7 benzaldehyde 
• 3580-38-9 2-Benzoylcyclohexanone 

Downstream Products

• 1421005-76-6 3-(2-cyanoethylsulfanyl)-1-phenyl-5,6,7,8-tetrahydroisoquinoline-4-carbonitrile 
• 332174-94-4 benzyl 2-(4-cyano-1-phenyl-5,6,7,8-tetrahydroisoquinolin-3-ylsulfanyl)acetate 
• 303786-36-9 (1-amino-5-phenyl-6,7,8,9-tetrahydrothieno[2,3-c]isoquinolin-2-yl)(phenyl)methanone 
• 1421005-88-0 3-[2-(3,4-dihydroxyphenyl)-2-oxoethylsulfanyl]-1-phenyl-5,6,7,8-tetrahydroisoquinoline-4-carbonitrile 

Relevant academic research and scientific papers

Cyanoselenoacetamide in a new synthesis of propane-bis(thioamide), the promising reagent for heterocyclizations

Cyanoselenoacetamide reacts with hydrogen sulfide to form propane-bis(thioamide), which can be used to produce thiazoles (the Hantzsch synthesis) and 3-thioxo-1-phenyl-2,3,5,6,7,8-hexahydroisoquinoline-4- carbonitrile. From the latter compound, 2-alkylsul

Synthesis and alkylation of 1-substituted 3-thioxo-2,3,5,6,7,8- hexahydroisoquinoline-4-carbonitriles

The condensation of cyclohexylidene(cyano)thioacetamides with aldehydes or of 2-acyl-1-(morpholin-4-yl)cycloalkenes with dithiomalonamide gave 1-alkyl(aryl)-3-thioxo-2,3,5,6,7,8-hexahydroisoquinoline-4-carbonitriles. Reactions of the latter with various a

CYCLIZATION OF NITRILES. X. ENAMINO NITRILES OF THE 1,3-DITHIA-4-CYCLOHEXENE SERIES AND THEIR RECYCLIZATION TO DERIVATIVES OF PYRIDINE AND THIAZOLE

The recyclization of 4-amino-6-aryl-5-cyano-2-cyclopentane(cyclohexane)spiro-1,3-dithia-4-cyclohexenes, obtained from gem-dithiols and arylidenemalononitriles, leads to the formation of 4-aryl-5,6-polymethylene-3-cyano-2-(1H)-pyridinethiones.The latter are used in the synthesis of various 3-aminothienopyridines, 4-aryl-3-amino-5,6,7,8-tetrahydrothienoquinolines, and other heterocyclic compounds condensed with quinoline. 1-Cyano-1-(4-aryl-2-thiazolyl)-2-arylethylenes were obtained by the reaction of the 1,3-dithia-4-cyclohexenes with phenacyl bromides.