94871-48-4

Upstream product

• 94-41-7 benzalacetophenone 
• 540-37-4 p-aminoiodobenzene 
• 100-52-7 benzaldehyde 
• 98-86-2 acetophenone 
• 13735-81-4 1-styrenyloxytrimethylsilane 
• 102904-39-2 (E)-1-phenyl-N-(4-iodophenyl)methanimine 

Relevant academic research and scientific papers

An Efficient Synthesis of 1,3-Diphenyl-3-phenylamino-propan-1-one and its Derivatives by Mannich Reaction in the Presence of Doped Porous Carbon by Nitrogen and Sulfur (NS-PCS) as Catalyst

Synthesis of β-amino carbonyl compounds by Mannich reaction involves the creation of various bonds in a single action and is attracting great attention as one of the most powerful synthetic tools for the expansion of molecular convolution and versatility. Carbon spheres (CSs) combine the advantages of carbon materials with spherical colloids, which gives them several inimitable features as catalysts. In this work, the reaction between acetophenone, aromatic aldehydes, and aromatic amines has been efficiently catalyzed by porous carbon spheres which were doped by nitrogen and sulfur (NS-PCS) at ambient temperature to give diverse β-amino carbonyl compounds in nearly high yields.

Reusable 1,2,4-triazolium based bronsted acidic room temperature ionic liquids as catalyst for mannich base reaction

Unprecedented examples of 1-alkyl-1,2,4-triazolium methanesulfonate based Bronsted acidic room temperature ionic liquids were synthesized and characterized. Their catalytic activity and efficiency in recyclability and reusability on one pot synthesis of halide substituted β-amino carbonyl compounds are reported. Graphical Abstract: [Figure not available: see fulltext.]

Ionic amino acids: Application as organocatalysts in the aza-Michael reaction

The ethyl methyl imidazolium salts of amino acids, [emim][AA], have been used as catalysts in the aza-Michael reaction. Furthermore, when chiral amino acids were used, a stereoselective reaction was achieved. The mechanism of the transformation was verified by the detection of a key intermediate by electrospray ionization mass spectroscopy (ESI-MS).

Cerium chloride (CeCl3·7H2O) as a highly efficient catalyst for one-pot three-component Mannich reaction

We have demonstrated the use of CeCl3·7H2O as highly efficient catalyst for one-pot threecomponent Mannich reaction to afford β-amino carbonyl compounds in good to excellent yield within shorter period of reaction time. The process is mild, efficient, environmentally benign with the use of little amount of catalyst.

Novel one-pot Cu-nanoparticles-catalyzed Mannich reaction

Recyclable heterogeneous Cu-nanoparticles efficiently catalyzed the one-pot three-component Mannich reaction of ketones, aromatic aldehydes and amines in methanol. This method provides a novel and improved method for obtaining β-amino carbonyl compounds in terms of good yield with little catalyst loading.

Mannich-type reactions in a colloidal solution formed by sodium tetrakis(3,5-trifluoromethylphenyl)borate as a catalyst in water

Sodium tetrakis(3,5-trifluoromethylphenyl)borate [NaBAr4F] efficiently catalyzed the one-pot, three-component Mannich reaction of ketones with aromatic aldehydes and different anilines in water at an ambient temperature and afforded the corresponding β-amino carbonyl compounds in good to excellent yields.

The Mannich reaction between aromatic ketones, aromatic aldehydes and aromatic amines

The acid-catalyzed Mannich reaction of acetophenones with benzaldehyde derivatives and aromatic amines gives 1,3-diaryl-3-(arylamino)propanones in high yield.

Secondary Mannich Bases via Trimethylsilyl Trifluoromethanesulphonate Promoted Addition of Silyl Enol Ethers to Schiff Bases

A convinient route to N-aryl-β-aminoketones is reported involving addition of silyl enol ethers to Schiff bases activated with 15 molpercent of trimethylsilyl trifluoromethanesulfonate.