94898-45-0Relevant academic research and scientific papers
Synthesis of substituted imidazolo[1,2-α]piperidinoses and their evaluation as glycosidase inhibitors
Dubost, Estelle,Le Nouen, Didier,Streith, Jacques,Tarnus, Celine,Tschamber, Theophile
, p. 610 - 626 (2007/10/03)
The synthesis of substituted imidazolo[1,2-α]-L-arabino-piperidinoses is reported. The substituents are methyl, phenylmethyl, phenylethyl, cyclohexylethyl, pyridinylethyl, piperidinylethyl, phenylpropyl and hydroxymethyl. All substituents are connected to
Increasing the inhibitory potency of L-arabino-imidazolo-[1,2]-piperidinose towards β-D-glucosidase and β-D-galactosidase
Dubost, Estelle,Tschamber, Théophile,Streith, Jacques
, p. 3667 - 3670 (2007/10/03)
The synthesis of some potent inhibitors of two retaining β-glycosidases was achieved by introducing aglycon-mimics into the imidazole moiety of L-arabino azasugar 1. The strongest inhibition was observed with the phenyl-ethyl substituent at C(2) of 1 agai
A Novel Transformation of Four Aldoses to Some Optically Pure Pseudohexopyranoses and a Pseudopentofuranose, Carboxylic Analogues of Hexopyranoses and Pentofuranose. Synthesis of Derivatives of (1S,2S,3R,4S,5S)-, (1S,2S,3R,4R,5S)-, (1R,2R,3R,4R,5S)-, (1S,
Tadano, Kin-ichi,Maeda, Hiroo,Hoshino, Masahide,Iimura, Youichi,Suami, Tetsuo
, p. 1946 - 1956 (2007/10/02)
Knoevenagel reactions with dimethyl malonate of the suitably protected acylic aldehydes 6, 20, 34, and 46, which were prepared from D-ribose, D-xylose, D-arabinose, and D-erythrose, respectively, proceeded smoothly to provide α,β-unsaturated diesters 7, 2
SYNTHESIS OF OPTICALLY ACTIVE PSEUDO-α-D-GLUCOSE AND PSEUDO-β-L-ALTROSE
Suami, Tetsuo,Tadano, Kin-ichi,Kameda, Yukiaki,Iimura, Youichi
, p. 1919 - 1922 (2007/10/02)
Optically active two pseudo-sugars, pseudo-α-D-glucose and pseudo-β-L-altrose have been synthesized by cyclization of 2,3,4-tri-O-benzyl-5-deoxy-5-iodo-L-arabinose with dimethyl malonate in the presence of sodium hydride as a key reaction.
