949-06-4

Basic information

• Product Name: 5-CHLORO-1-(4-METHOXYPHENYL)-1-OXOPENTANE
• Synonyms: 5-CHLORO-1-(4-METHOXYPHENYL)-1-OXOPENTANE
• CAS NO: 949-06-4
• Molecular Formula: C₁₂H₁₅ClO₂
• Molecular Weight: 226.7
• Mol File: 949-06-4.mol

Chemical Properties

• Boiling Point: 357.051°C at 760 mmHg
• Flash Point: 146.821°C
• Appearance: /
• Density: 1.101g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.511
• CAS DataBase Reference: 5-CHLORO-1-(4-METHOXYPHENYL)-1-OXOPENTANE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-CHLORO-1-(4-METHOXYPHENYL)-1-OXOPENTANE(949-06-4)
• EPA Substance Registry System: 5-CHLORO-1-(4-METHOXYPHENYL)-1-OXOPENTANE(949-06-4)

Safety Data

• Hazardous Substances Data: 949-06-4(Hazardous Substances Data)

Usage

InChI:InChI=1/C12H15ClO2/c1-15-11-7-5-10(6-8-11)12(14)4-2-3-9-13/h5-8H,2-4,9H2,1H3

Upstream product

• 6280-87-1 δ-chlorovaleronitrile 
• 13139-86-1 4-methoxyphenyl magnesium bromide 
• 1575-61-7 5-Chlorovaleroyl chloride 
• 100-66-3 methoxybenzene 
• 120-92-3 cyclopentanone 
• 1119-46-6 5-chloro-valeric acid 

Downstream Products

• 120589-98-2 hexahydro-1,3-dimethyl-8a-(4-methoxyphenyl)<1,2,4>triazolo<1,5-a>pyridine-2(3H)-thione 
• 26954-35-8 1-(4-methoxyphenyl)pent-4-en-1-one 
• 100-06-1 1-(4-methoxyphenyl)ethanone 
• 276873-26-8 1-(4-methoxy-phenyl)-5-(9H-purin-6-ylsulfanyl)-pentan-1-one 
• 282116-67-0 ethyl 7-chloro-3-hydroxy-3-(4-methoxyphenyl)-heptanoate 
• 226920-45-2 4-phthalimido-1-(4'-methoxy-phenyl)-pentan-1-one 
• 58012-91-2 5-[4-(α-hydroxy-α-phenylbenzyl)piperidino]-4'-methoxyvalerophenone hydrochloride 

Relevant articles and documents

Catalytic Ring-Opening of Cyclic Alcohols Enabled by PCET Activation of Strong O-H Bonds

We report a new photocatalytic protocol for the redox-neutral isomerization of cyclic alcohols to linear ketones via C-C bond scission. Mechanistic studies demonstrate that key alkoxy radical intermediates in this reaction are generated via the direct homolytic activation of alcohol O-H bonds in an unusual intramolecular PCET process, wherein the electron travels to a proximal radical cation in concert with proton transfer to a weak Br?nsted base. Effective bond strength considerations are shown to accurately forecast the feasibility of alkoxy radical generation with a given oxidant/base pair.

Novel compound capable of activating Nrf2, and pharmaceutical compositions comprising the same

The present invention provides a novel compound which can activate Nrf2 that is a transcription factor for expression of the quinone reductase gene. Therefore the compound is effective for inhibiting apoptosis and preventing and treating brain nerve disea

THIOPYRAN COMPOUNDS AS INHIBITORS OF MMP

A compound of formula (I) in which R is lower alkyl, halogen, optionally substituted heterocyclic group or optionally substituted aryl, R is carboxy, protected carboxy or amidated carboxy, Ar is optionally substituted aryl or optionally substituted heterocyclic group, A is lower alkylene, X is oxa or a single bond, Y is thia, sulfinyl or sulfonyl, Z is methylene, thia, sulfinyl or sulfonyl, m and n are each an integer of 0 to 6, and 1/=m+n/=6, or its salt, which is useful as an inhibitor of matrix metalloproteinases (MMP) or tumor necrosis factor alpha (TNF alpha ).

PREVENTIVES/REMEDIES FOR URINARY DISTURBANCE

Preventives/remedies for voiding disturbance containing a compound having both of an acetylcholinesterase inhibitory action and an α1 antagonistic action which exhibits an excellent effect of improving the urinary function of the bladder (i.e., effects of

Synthesis and some properties of 6-(ω-aroylbutylthio)purines

A series of 6-(ω-aroylthio)purines, which have not been described in the literature, has been obtained by the reaction of 6-purinethione with ω-chlorovalerophenone and its substituted derivatives. Some properties of the compounds synthesized have been studied, viz. reaction at the carbonyl group, methylation, and hydrolysis. 1999 KluwerAcademic/Plenum Publishers.