94914-32-6Relevant articles and documents
BICYCLIC JAK INHIBITORS AND USES THEREOF
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Paragraph 000341, (2020/10/20)
Provided herein are compounds of Formulas (I), (II), (III), and (IV) and subformulas thereof, wherein the variables are defined herein. Also provided herein are pharmaceutical compositions comprising a compound of Formula (I), (II), (III), or (IV) and methods of using the compounds, e.g., in the treatment of immune disorders, inflammatory disorders, and cancer.
A one-pot selective synthesis of N-Boc protected secondary amines: Tandem direct reductive amination/N-Boc protection
Neelarapu, Raghupathi,Petukhov, Pavel A.
scheme or table, p. 7056 - 7062 (2012/08/28)
A one-pot tandem direct reductive amination of aldehydes with primary amines resulting in N-Boc secondary amines using a (Boc)2O/sodium triacetoxyborohydride (STAB) system is reported. The tandem procedure is efficient, selective, and versatile, giving excellent yields of N-Boc protected secondary amines even in those cases where the products are prone to intramolecular lactamization.
