951885-14-6

Basic information

• Product Name: N-butyl 5-bromopyridine-2-carboxamide
• Synonyms: N-Butyl 5-bromopicolinamide;N-butyl 5-bromopyridine-2-carboxamide
• CAS NO: 951885-14-6
• Molecular Formula: C₁₀H₁₃BrN₂O
• Molecular Weight: 257.13
• Product Categories: blocks;Bromides;Carboxes;Pyridines
• Mol File: 951885-14-6.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: N-butyl 5-bromopyridine-2-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-butyl 5-bromopyridine-2-carboxamide(951885-14-6)
• EPA Substance Registry System: N-butyl 5-bromopyridine-2-carboxamide(951885-14-6)

Safety Data

• Hazardous Substances Data: 951885-14-6(Hazardous Substances Data)

Usage

General Description

N-butyl 5-bromopyridine-2-carboxamide is a chemical compound derived from the combination of N-butyl and 5-bromopyridine-2-carboxamide. It is commonly used in pharmaceutical research and development as a building block in the synthesis of novel pharmaceutical compounds. N-butyl 5-bromopyridine-2-carboxamide has the potential to exhibit biological activity and is often used as a starting material in the creation of new drugs. Its unique chemical structure makes it valuable for medicinal chemistry and drug discovery efforts. Additionally, it may have applications in other fields such as agrochemicals and material science. Its synthesis and properties make it an important chemical for both scientific research and practical applications.

Upstream product

• 137178-88-2 5-bromopyridine-2-carbonyl chloride 
• 109-73-9 N-butylamine 
• 30766-11-1 5-bromoisonicotinic acid 

Relevant articles and documents

Iridium(III)-Catalyzed Regioselective Intermolecular Unactivated Secondary Csp3?H Bond Amidation

For the first time, a highly regioselective intermolecular sulfonylamidation unactivated secondary Csp3?H bond has been achieved using IrIIIcatalysts. The introduced N,N’-bichelating ligand plays a crucial role in enabling iridium–nitrene insertion into a secondary Csp3?H bond via an outer-sphere pathway. Mechanistic studies and density functional theory (DFT) calculations demonstrated that a two-electron concerted nitrene insertion was involved in this Csp3?H amidation process. This method tolerates a broad range of linear and branched-chain N-alkylamides, and provides efficient access to diverse γ-sulfonamido-substituted aliphatic amines.