951889-08-0Relevant academic research and scientific papers
6-Arylphenanthridines from Aryl o-Biaryl Ketones with 1,1,1,3,3,3-Hexamethyldisilazane and Molecular Iodine
Kobayashi, Eiji,Kishi, Atsushi,Togo, Hideo
, p. 7335 - 7347 (2019/11/22)
Warming treatment of aryl o-biaryl ketones with 1,1,1,3,3,3-hexamethyldisilazane in the presence of Sc(OTf)3 in toluene, followed by the reaction with molecular iodine and K2CO3 in a mixture of THF and methanol at 60 °C gave the corresponding 6-arylphenanthridines in good to moderate yields. The present reaction is a one-pot method for the preparation of 6-arylphenanthridines from aryl o-biaryl ketones through the cyclization of imino-nitrogen-centered radicals that were generated from N-iodo aryl o-biaryl ketimines formed from the reaction of aryl biaryl ketimines with molecular iodine.
Palladium(II)-catalyzed Intermolecular Cascade Cyclization of Methylenecyclopropanes with Aromatic Alkynes: Construction of Spirocyclic Compounds Containing Indene and 1,2-Dihydronaphthalene Moieties
Fang, Wei,Wei, Yin,Shi, Min
, (2019/05/22)
A palladium(II)-catalyzed intermolecular cascade cyclization of methylenecyclopropanes with aromatic alkynes is reported in this paper. The reaction involves a migratory insertion of alkyne, an intramolecular Heck-type reaction, and β-H elimination, providing a series of spirocyclic compounds containing indene and 1,2-dihydronaphthalene moieties in moderate to excellent yields upon heating.
Dibenzo [c, i] [1,10] O-phenanthroline and its derivatives and preparation method
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Paragraph 0043-0045, (2017/01/26)
The invention discloses a dibenzo[c, i][1, 10]o-phenanthroline, its derivative and preparation method. The compound is characterized in that: two phenanthridines share a benzene ring, and the ortho-position of the nitrogen atom is equipped with a substituent group, which can be hydrogen, alkyl, phenyl or aryl. The preparation method includes: taking 4, 7-dibromobenzo[2, 1, 3]thiadiazole and 2-formyl phenylboronic acid or 2-acetyl(or arylformyl)phenylboronic acid pinacol ester as raw materials, carrying out Suzuki coupling reaction to obtain a series of 4, 7-di[2-formyl, 2-alkylformyl or arylformyl]benzo[2, 1, 3]thiadiazole, and finally carrying out reduction by sodium borohydride/cobalt chloride hexahydrate or lithium aluminum hydride and cyclization so as to obtain a series of dibenzo[c, i][1, 10]o-phenanthroline and its derivatives. The series of organic compounds provided by the invention broadens the scope of organic electroluminescent materials, and the preparation method provides a simple and convenient way for synthesis of phenanthroline series compounds. (formula).
Convenient method for the synthesis of phthalazinones via carbonylation of 2-bromobenzaldehyde using Co2(CO)8 as a CO source
Suresh, A. Sivalingam,Baburajan, Poongavanam,Ahmed, Mansur
supporting information, p. 3482 - 3485 (2014/06/10)
A simple one-pot synthesis of phthalazinones by the condensation and intra-molecular carbonylative cyclization of 2-bromobenzaldehydes with hydrazines is reported. This method utilizes solid Co2(CO) 8 as carbonyl source making it rea
Synthesis of 1,3-Diaryl-2-methoxyindenes by hydriodic acid-catalyzed cyclization of Aryl[2-(1-aryl-2-methoxyvinyl)phenyl]methanols
Kobayashi, Kazuhiro,Shirai, Yuu,Nagaoka, Toshiyuki,Konishi, Hisatoshi
experimental part, p. 2866 - 2881 (2009/12/03)
An efficient two-step method for the synthesis of 1,3-diaryl-2- methoxyindenes from 1-(1-aryl-2-methoxyvinyl)-2-bromobenzenes has been developed. Thus, the reaction of 2-(1-aryl-2-methoxyvinyl)phenyllithiums, generated in situ by halogen-lithium exchange between 1-(1-aryl-2-methoxyvinyl)- 2-bromobenzenes and butyllithium, with aromatic aldehydes gives aryl[2-(1-aryl-2-methoxyvinyl)phenyl]methanols, which in turn are treated with a catalytic amount of concentrated hydriodic acid to afford the corresponding 1,3-diaryl-2-methoxyindenes in reasonable yields.
