95191-56-3

Upstream product

• 1498-64-2 O-ethyl dichlorothiophosphate 
• 108-95-2 phenol 
• 64-17-5 ethanol 
• 18961-96-1 O-phenylphosphorodichloridothioate 
• 32345-29-2 O,O-diethyl-O-phenyl phosphorothioate 

Downstream Products

• 33529-25-8 C₉H₁₅N₂O₄PS₂ 
• 33529-26-9 C₁₅H₁₉N₂O₄PS₂ 
• 135492-39-6 (5-Methyl-6-oxo-5,6-dihydro-1H-[1,2,4]triazin-4-yl)-phosphonothioic acid O-ethyl ester O-phenyl ester 
• 160422-77-5 O-ethyl-O-phenylisothiocyanatothiophosphate 
• 1240409-91-9 O-ethyl, O-phenyl, O-(Z-[1-phenyl-2-(1H-1,2,4-triazol-1-yl)ethylidene]amino) phosphorothioate 
• 1381809-23-9 C₂₈H₂₅N₂O₇PS 
• 69322-82-3 [1-Amino-eth-(Z)-ylidene]-thiophosphoramidic acid O-ethyl ester O'-phenyl ester 
• 41315-37-1 C₉H₁₄NO₃PS 

Relevant academic research and scientific papers

A new convenient synthesis of phosphoro(-no)chloridothionates

A general procedure for synthesis of phosphoro(-no)chlorides, particularly unsymmetrical ones, has been developed. The method involves the dealkylation of O,O-dialkyl phosphoro(-no)thionates 1 with dimethylamine and the chlorination of O-alkyl ammonium phosphoro(-no)thioates 2 using phosphorus oxychloride as a chlorinating agent.

Kinetics and mechanism of the aminolysis of aryl ethyl chloro and chlorothio phosphates with anilines

The reactions of ethyl Y-phenyl chloro (1) and chlorothio (2) phosphates with X-anilines in acetonitrile at 55.0 °C are studied kinetically and theoretically. Kinetic results yield the primary kinetic isotope effects (k H/kD = 1.07-1.80 and 1.06-1.27 for 1 and 2, respectively) with deuterated aniline (XC6H4ND2) nucleophiles, and the cross-interaction constants ρXY = -0.60 and -0.28 for 1 and 2, respectively. A concerted mechanism involving a partial frontside attack through a hydrogen-bonded, four-center-type transition state is proposed. The large ρX (ρnuc = -3.1 to -3.4) and βX (βnuc = 1.1-1.2) values seem to be characteristic of the anilinolysis of phosphates and thiophosphates with the Cl leaving group. Because of the relatively large size of the aniline nucleophile, the degree of steric hindrance could be the decisive factor that determines the direction of the nucleophilic attack to the phosphate and thiophosphate substrates with the relatively small-sized Cl leaving group. This journal is The Royal Society of Chemistry.

Synthesis of N-(thio)phosphoryl-N′-2-benzoxazolyl semicarbazides

We prepared the benzoxazole derivatives bearing the (thio) phosphoryl moiety by addition reactions of 2-hydrazionbenzoxazole with isothiocyanato (thio) phosphates and characterized their structures by elementary analysis and 1H NMR and IR spectral data. From the results of biological activity screening, we found that these compounds possess some herbicidal, and plant growth regulator activities, and especially good fungicidal activity against Puccinia recondita.