952202-65-2

Upstream product

• 952202-64-1 3-bromo-2-oxo-2H-chromen-4-yl trifluoromethanesulfonate 
• 5720-07-0 4-methoxyphenylboronic acid 
• 2650-14-8 3-bromo-4-hydroxycoumarin 
• 1076-38-6 4-hydroxy[1]benzopyran-2-one 
• 33397-21-6 tris(4-methoxyphenyl)bismuth 
• 1452154-65-2 phenyl 3-(4-methoxyphenyl)propiolate 

Downstream Products

• 2132-80-1 4,4'-Dimethoxybiphenyl 
• 128836-59-9 4,4'-Diisopropoxy-biphenyl 

Relevant academic research and scientific papers

Synthesis of Polycyclic Heteroaromatic Coumarins via Photoinduced Dehydrogenative Annulation of 4-Phenyl-3-heteroarylcoumarins

An efficient, oxidant and metal-free synthesis of polycyclic heteroaromatic coumarins was developed. H-Furo[2′,3′:3,4]naphtho[2,1-c]chromen-4-one (2a-2f), 1H-benzofuro[2′,3′:3,4]naphtho[2,1-c]chromen-1-one (2g-2j), and 4H-thieno[2′,3′:3,4]naphtho[2,1-c]ch

Synthesis of: Cis / trans -dihydrochromenones via a photoinduced rearrangement of 4-phenyl-3-aryl/cyclohexenylcoumarins

A concise and environmentally friendly protocol has been developed for the synthesis of cis-dihydrochromenones and trans-dihydrochromenones in EtOH at room temperature. Irradiation of 4-phenyl-3-arylcoumarins in EtOH with 313 nm UV light under an argon atmosphere at room temperature gave cis-4b,15c-dihydro-16H-benzofuro[3′,2′:7,8]phenanthro[9,10-c]chromen-16-ones and cis-8c,14b-dihydro-9H-benzo[11,12]chryseno[5,6-c]chromen-9-ones in good yields. And an analogous treatment of 4-phenyl-3-alkenylcoumarins as 4-phenyl-3-arylcoumarins provided trans-1,2,3,4,4a,14b-hexahydro-5H-phenanthro[9,10-c]chromen-5-ones. The described photorearrangement proceeded smoothly without the addition of any transition metals and additives. The photorearrangement of 4-phenyl-3-arylcoumarins is believed to proceed via 6π-electrocyclization, a [1,3]-hydrogen shift and keto-enol isomerization.

Visible-light-mediated radical cascade reaction: Synthesis of 3-bromocoumarins from alkynoates

A visible-light-mediated radical addition of alkynoates to generate 3-bromocoumarins by using N-bromosuccinimide as the bromo source has been accomplished. This procedure provides a bromo radical addition/spirocyclization/ester migration cascade reaction

Pd-catalyzed cross-coupling study of bi-functional 3-bromo-4-trifloxycoumarins with triarylbismuth reagents

Abstract The cross-coupling reactions of functionalized 3-bromo-4-trifloxycoumarins have been explored with threefold arylating triarylbismuth reagents. These palladium-catalyzed reactions afforded chemo-selective C-4 arylations with the facile formation of 3-bromo-4-arylcoumarins in good to high yields. Additionally, palladium-catalyzed arylations of functionalized 3-bromo-4-arylcoumarins also participated in the second arylation to give functionalized 3,4-diarylcoumarins in high yields.

General and efficient route for the synthesis of 3,4-disubstituted coumarins via Pd-catalyzed site-selective cross-coupling reactions

(Chemical Equation Presented) Palladium-catalyzed site-selective cross-coupling reactions of 3-bromo-4-trifloxycoumarin or 3-bromo-4- tosyloxycoumarin provide an efficient and facile route for the synthesis of 3,4-disubstituted coumarins, which include 3,