952686-29-2

Upstream product

• 817573-86-7 (3R,7S,8S,8aR)-8-ethyl-7-(2-indolylmethyl)-5-oxo-3-phenyl-2,3,6,7,8,8a-hexahydro-5H-oxazolo[3,2-a]pyridine 
• 755759-06-9 (3R,7S,8S,8aR)-8-ethyl-7-[2-(2-indolyl)-1,3-dithiolan-2-yl]-5-oxo-3-phenyl-2,3,6,7,8,8a-hexahydro-5H-oxazolo[3,2-a]pyridine 
• 457622-91-2 (3R,8S,8aR)-8-ethyl-5-oxo-3-phenyl-2,3,8,8a-tetrahydro-5H-oxazolo[3,2-a]pyridine 
• 115127-30-5 2-(1',3'-Dithian-2'-yl)indole 

Relevant academic research and scientific papers

Enantioselective synthesis of 2-[(3-ethyl-4-piperidyl)methyl]indoles from a phenylglycinol-derived lactam: formal synthesis of Strychnos alkaloids

A diastereodivergent synthesis of enantiopure cis- and trans-2-[(3-ethyl-4-piperidyl)methyl]indole (cis-1b and trans-1b) from a common phenylglycinol-derived oxazolopiperidone lactam 3 is reported. The key step is a stereocontrolled conjugate addition, ei