817573-86-7Relevant academic research and scientific papers
Enantioselective synthesis of 2-[(3-ethyl-4-piperidyl)methyl]indoles from a phenylglycinol-derived lactam: formal synthesis of Strychnos alkaloids
Amat, Mercedes,Llor, Núria,Checa, Bego?a,Pérez, Maria,Bosch, Joan
, p. 6722 - 6725 (2008/02/13)
A diastereodivergent synthesis of enantiopure cis- and trans-2-[(3-ethyl-4-piperidyl)methyl]indole (cis-1b and trans-1b) from a common phenylglycinol-derived oxazolopiperidone lactam 3 is reported. The key step is a stereocontrolled conjugate addition, ei
Conjugate additions to phenylglycinol-derived unsaturated δ-lactams. Enantioselective synthesis of uleine alkaloids
Amat, Mercedes,Perez, Maria,Llor, Nuria,Escolano, Carmen,Luque, F. Javier,Molins, Elies,Bosch, Joan
, p. 8681 - 8693 (2007/10/03)
The stereochemical outcome of the conjugate addition of a variety of stabilized nucleophiles (2-indoleacetic enolates and sulfur-stabilized anions) to the phenylglycinol-derived unsaturated lactams trans-2, cis-2, and its 8-ethyl-substituted analogue 10 i
