755759-06-9Relevant academic research and scientific papers
Enantioselective synthesis of 2-[(3-ethyl-4-piperidyl)methyl]indoles from a phenylglycinol-derived lactam: formal synthesis of Strychnos alkaloids
Amat, Mercedes,Llor, Núria,Checa, Bego?a,Pérez, Maria,Bosch, Joan
, p. 6722 - 6725 (2008/02/13)
A diastereodivergent synthesis of enantiopure cis- and trans-2-[(3-ethyl-4-piperidyl)methyl]indole (cis-1b and trans-1b) from a common phenylglycinol-derived oxazolopiperidone lactam 3 is reported. The key step is a stereocontrolled conjugate addition, ei
Enantioselective formal synthesis of uleine alkaloids from phenylglycinol-derived bicyclic lactams
Amat, Mercedes,Perez, Maria,Llor, Nuria,Martinelli, Marisa,Molins, Elies,Bosch, Joan
, p. 1602 - 1603 (2007/10/03)
A two-step route for the enantioselective construction of the tetracyclic ring system of uleine alkaloids, involving the stereoselective conjugate addition of an appropriate indole-containing nucleophile to a chiral bicyclic δ-lactam and the subsequent cy
Conjugate additions to phenylglycinol-derived unsaturated δ-lactams. Enantioselective synthesis of uleine alkaloids
Amat, Mercedes,Perez, Maria,Llor, Nuria,Escolano, Carmen,Luque, F. Javier,Molins, Elies,Bosch, Joan
, p. 8681 - 8693 (2007/10/03)
The stereochemical outcome of the conjugate addition of a variety of stabilized nucleophiles (2-indoleacetic enolates and sulfur-stabilized anions) to the phenylglycinol-derived unsaturated lactams trans-2, cis-2, and its 8-ethyl-substituted analogue 10 i
