953039-66-2 Usage
Uses
Used in Medicinal Chemistry:
7-Bromo-2-chloroquinazoline is used as a pharmaceutical candidate for the development of new drugs due to its biological activity and potential to treat various diseases.
Used in Agrochemicals:
7-Bromo-2-chloroquinazoline is used as an active ingredient in the development of agrochemicals, such as pesticides and herbicides, to protect crops from pests and diseases.
Used in Chemical Synthesis:
7-Bromo-2-chloroquinazoline is used as a building block in the preparation of other organic compounds, contributing to the synthesis of complex molecules for various applications.
Used in Pharmaceutical Development:
7-Bromo-2-chloroquinazoline is used as a key intermediate in the synthesis of new pharmaceuticals, enabling the development of innovative treatments for a range of medical conditions.
Overall, 7-Bromo-2-chloroquinazoline is a valuable chemical compound with diverse applications across different industries, particularly in the fields of medicine and industrial chemistry. Its unique structure and properties make it a promising candidate for further research and development.
Check Digit Verification of cas no
The CAS Registry Mumber 953039-66-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,5,3,0,3 and 9 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 953039-66:
(8*9)+(7*5)+(6*3)+(5*0)+(4*3)+(3*9)+(2*6)+(1*6)=182
182 % 10 = 2
So 953039-66-2 is a valid CAS Registry Number.
InChI:InChI=1/C8H4BrClN2/c9-6-2-1-5-4-11-8(10)12-7(5)3-6/h1-4H
953039-66-2Relevant academic research and scientific papers
NOVEL 6-6 BICYCLIC AROMATIC RING SUBSTITUTED NUCLEOSIDE ANALOGUES FOR USE AS PRMT5 INHIBITORS
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, (2017/03/14)
The present invention relates novel 6-6 bicyclic aromatic ring substituted nucleoside analogues of Formula (I) wherein the variables have the meaning defined in the claims. The compounds according to the present invention are useful as PRMT5 inhibitors. The invention further relates to pharmaceutical compositions comprising said compounds as an active ingredient as well as the use of said compounds as a medicament.
Novel Mps1 kinase inhibitors: From purine to pyrrolopyrimidine and quinazoline leads
Bursavich, Matthew G.,Dastrup, David,Shenderovich, Mark,Yager, Kraig M.,Cimbora, Daniel M.,Williams, Brandi,Kumar, D. Vijay
, p. 6829 - 6833 (2014/01/06)
Mps1, also known as TTK, is a mitotic checkpoint protein kinase that has become a promising new target of cancer research. In an effort to improve the lead-likeness of our recent Mps1 purine lead compounds, a scaffold hopping exercise has been undertaken.
QUINAZOLINES FOR PDK1 INHIBITION
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, (2008/06/13)
The invention provides novel quinazoline compounds that are inhibitors of PDK1. Also provided are pharmaceutical compositions including the compounds, and methods of treating proliferative diseases, such as cancers, with the compounds or compositions.
