95338-12-8Relevant academic research and scientific papers
Stereocontrolled synthesis of all eight stereoisomers of the putative anti-androgen cyoctol
Mulzer, Johann,Kaselow, Ulrich,Graske, Klaus-Dieter,Kühne, Holger,Sieg, Andreas,Martin, Harry J.
, p. 9599 - 9614 (2007/10/03)
All eight stereoisomers (1-4 and enantiomers) of the putative anti-androgen cyoctol have been synthesized along stereochemically unambiguous routes. The biological tests of all isomers indicated that cyoctol is not an anti-androgen, contrary to the patent literature. All eight stereoisomers of the putative anti-androgen cyoctol have been prepared and tested biologically.
Carbon Hydroxylation of Alkyltetrahydropyranols: A Paradigm for Spiroacetal Biosynthesis in Bactrocera sp.
Stok, Jeanette E.,Lang, Cheng-Shan,Schwartz, Brett D.,Fletcher, Mary T.,Kitching, William,De Voss, James J.
, p. 397 - 400 (2007/10/03)
(Equation Presented) In a number of Bactrocera species the penultimate step in the biosynthesis of spiroacetals is shown to be the hydroxylation of an alkyltetrahydropyranol followed by cyclization. The monooxygenases that catalyze this side chain hydroxy
A New Catalytic Asymmetric Approach to Polyfunctional Aldol Products Mediated by Zinc Organometallics.
Knochel, Paul,Brieden, Walter,Rozema, Michael J.,Eisenberg, Christina
, p. 5881 - 5884 (2007/10/02)
The catalytic asymmetric addition of functionalized dialkylzincs to β-alkoxyaldehydes provides after a short sequence of functional group interconversions aldol products in 40-99 percentee.Their stereoselective transformation to either syn- or anti-1,3-di
SYNTHESIS OF ALL OF THE FOUR ENERGETICALLY POSSIBLE STEREOISOMERS OF 7-ETHYL-2-METHYL-1,6-DIOXASPIRODECANE; A PHEROMONE PRODUCED BY BEES PARAVESPURA VULGARIS L. AND ANDRENA HAEMORRHOA F.
Mori, Kenji,Ikunaka, Masaya
, p. 3471 - 3480 (2007/10/02)
All of the four energetically possible stereoisomers of 7-ethyl-2-methyl-1,6-dioxaspirodecane were synthesized starting from ethyl (S)-lactate and dimethyl (S)-malate or methyl (R)-β-hydroxy-valerate employing dianion alkylation as the key-step.
