95349-84-1Relevant academic research and scientific papers
Metal-Free-Visible Light C-H Alkylation of Heteroaromatics via Hypervalent Iodine-Promoted Decarboxylation
Genovino, Julien,Lian, Yajing,Zhang, Yuan,Hope, Taylor O.,Juneau, Antoine,Gagné, Yohann,Ingle, Gajendra,Frenette, Mathieu
, p. 3229 - 3232 (2018)
A metal-free photoredox C-H alkylation of heteroaromatics from readily available carboxylic acids using an organic photocatalyst and hypervalent iodine reagents under blue LED light is reported. The developed methodology tolerates a broad range of functional groups and can be applied to the late-stage functionalization of drugs and drug-like molecules. The reaction mechanism was investigated with control experiments and photophysical experiments as well as DFT calculations.
CONDENSATION OF ALDEHYDES AND KETONES. XXIII. ALKALINE CONDENSATION OF ACETOPHENONE WITH ISOBUTYRALDEHYDE
Tilichenko, M. N.,Akimova, T. I.,Buglak, E. I.
, p. 2378 - 2380 (2007/10/02)
The reaction of acetophenone with isobutyraldehyde in aqueous alcohol solutions of alkali leads to 4-benzoyl-3-isopropyl-6-methyl-1-phenyl-5-hepten-1-one.The reaction take place differently in an alkaline water-DMSO solution. (3-Isopropyl-1,5-diphenyl-1,5
