953786-52-2

Upstream product

• 909766-98-9 4-benzyloxy-6-iodo-2,3-dimethoxybenzaldehyde 

Downstream Products

• 953786-59-9 (R)-2-(4-(benzyloxy)-6-iodo-2,3-dimethoxyphenyl)-1-((3R,5S)-5-tert-butyldimethylsilyloxy-3-(triethylsilyloxy)cyclopent-1-enyl)ethanol 
• 953786-54-4 2-(4-(benzyloxy)-6-iodo-2,3-dimethoxyphenyl)-N-methoxy-N-methylacetamide 
• 953786-50-0 (S)-3-((S)-2-(4-(benzyloxy)-6-iodo-2,3-dimethoxyphenyl)-1-chloroethyl)-4-(tert-butyldimethylsilyloxy)cyclopent-2-enone 
• 953786-65-7 (1R,4S)-3-((S)-2-(4-(benzyloxy)-6-iodo-2,3-dimethoxyphenyl)-1-chloroethyl)-4-(tert-butyldimethylsilyloxy)cyclopent-2-enol 
• 953786-60-2 (S)-2-(4-(benzyloxy)-6-iodo-2,3-dimethoxyphenyl)-1-((3R,5S)-5-tert-butyldimethylsilyloxy-3-(triethylsilyloxy)cyclopent-1-enyl)-1-chloroethane 
• 953786-58-8 2-(4-(benzyloxy)-6-iodo-2,3-dimethoxyphenyl)-1-((3R,5S)-5-tert-butyldimethylsilyloxy-3-(triethylsilyloxy)cyclopent-1-enyl)ethanone 

Relevant academic research and scientific papers

Synthesis of the acutumine spirocycle via a radical-polar crossover reaction

A new radical-polar crossover reaction was developed that consists of intramolecular conjugate addition of an aryl radical followed by enolate formation and hydroxylation. A C-C bond, a C-O bond, and two congested stereocenters are created in the process.