95465-74-0Relevant academic research and scientific papers
Neutral-eosin Y-catalyzed regioselective hydroacylation of aryl alkenes under visible-light irradiation
Liu, Haiwang,Xue, Fei,Wang, Mu,Tang, Xinxin,Wu, Jie
supporting information, p. 406 - 410 (2020/12/30)
Styrene derivatives were hydroacylated with exclusive anti-Markovnikov selectivity by using neutral eosin Y as a direct hydrogen-atom-transfer (HAT) catalyst under visible-light irradiation. Aldehydes and styrenes with various substituents were tolerated (>20 examples), giving the corresponding products in moderate to high yields. The key acyl radical intermediate was generated from a direct HAT process induced by photoexcited eosin Y. Subsequent addition to styrenes and a reverse HAT process generated the ketone products.
Visible-Light-Promoted Photocatalyst-Free Hydroacylation and Diacylation of Alkenes Tuned by NiCl2·DME
Zhao, Xinxin,Li, Bing,Xia, Wujiong
, p. 1056 - 1061 (2020/02/15)
Herein, we describe a visible light-promoted hydroacylation strategy that facilitates the preparation of ketones from alkenes and 4-acyl-1,4-dihydropyridines via an acyl radical addition and hydrogen atom transfer pathway under photocatalyst-free conditions. The efficiency was highlighted by wide substrate scope, good to high yields, successful scale-up experiments, and expedient preparation of highly functionalized ketone derivatives. In addition, this protocol allows for the synthesis of 1,4-dicarbonyl compounds through alkene diacylation in the presence of NiCl2·DME.
Ketone Synthesis by Direct, Orthogonal Chemoselective Hydroacylation of Alkenes with Amides: Use of Alkenes as Surrogates of Alkyl Carbanions
Geng, Hui,Huang, Pei-Qiang
supporting information, (2019/07/08)
Direct functionalization of alkenes and direct transformation of carboxamides are two exciting areas that have attracted considerable attention in recent years. We report herein that secondary amides, the least reactive derivatives of carbonyl compounds, upon activated with triflic anhydride, can serve as effective hydroacylating reagents in partner with alkenes to yield ketones at ambient temperature. The method was applied to the one-step synthesis of racemic dihydro-ar-turmerone. In this method, alkenes serve as surrogates of organometallic reagents, which allows the orthogonal chemoselective reactions. The ready availability of many olefins such as camphene and norbornene permits one-step ketone synthesis that would require several steps by conventional methods.
Laser Flash Photolysis Study of the Photochemistry of Ring-Substituted β-Phenylpropiophenones
Netto-Ferreira, J. C.,Leigh, W. J.,Scaiano, J. C.
, p. 2617 - 2622 (2007/10/02)
The triplet states of an extensive series of ring-substituted β-phenylpropiophenones have been characterized by phosphorescence emission spectroscopy and in laser flash photolysis studies.Substitution in the β-phenyl ring has only a small effect on the tr
