955016-79-2Relevant academic research and scientific papers
A combination of copper(0) powder and selectfluor enables generation of cationic copper species for mild 1,2-dicarbonylation of alkynes
Zhang, Wenxia,Zhang, Jian,Liu, Yunkui,Xu, Zhenyuan
supporting information, p. 2709 - 2714 (2014/01/06)
A combination of copper powder and Selectfluor permits the generation of cationic copper species that efficiently catalyze 1,2-dicarbonylation of alkynes under mild conditions with water and dioxygen as inexpensive and environmentally benign sources of oxygen. Georg Thieme Verlag Stuttgart New York.
Synthesis, antileukemic and antiplatelet activities of 2,3-diaryl-6,7-dihydro-5H-1,4-diazepines
Ramajayam,Giridhar, Rajani,Yadav,Balaraman,Djaballah, Hakim,Shum, David,Radu, Constantin
, p. 2004 - 2010 (2008/12/22)
The synthesis, antileukemic and antiplatelet activity evaluation of 2,3-diaryl-6,7-dihydro-5H-1,4-diazepines are described. In general, it was found that compound 17o showed moderate antileukemic activity against MOLT3 human leukemic cancer cell lines. An arachidonic acid induced platelet aggregation effect on washed rat platelets was studied. Compound 17i was found to be the most potent. The antiplatelet properties may be mediated by interference with the arachidonic acid pathway.
Synthesis of novel substituted diaryl-1,4-diazepines
Ramajayam,Giridhar, Rajani,Yadav
, p. 901 - 906 (2008/02/12)
In this paper a convenient route to new 2,3-diaryl-substituted 1,4-diazepines is described through cyclization of ethanedione derivatives and 1,3-propanediamine. The ethanedione derivatives required were synthesized by microwave-assisted oxidation from ethanones.
