95652-80-5 Usage
General Description
2-Chloro-6-methoxynicotinaldehyde is a chemical compound with the formula C8H7ClNO2. It is a white to slightly yellow crystalline powder that is used in the pharmaceutical industry as an intermediate in the synthesis of various drugs. It is also used as a building block in the production of insecticides and herbicides. The compound is characterized by its aromatic, aldehyde, and halogen functional groups, making it a versatile building block for the synthesis of various organic molecules. It is important to handle this compound with care, as it is considered harmful if swallowed and can cause skin and eye irritation upon contact.
Check Digit Verification of cas no
The CAS Registry Mumber 95652-80-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,5,6,5 and 2 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 95652-80:
(7*9)+(6*5)+(5*6)+(4*5)+(3*2)+(2*8)+(1*0)=165
165 % 10 = 5
So 95652-80-5 is a valid CAS Registry Number.
InChI:InChI=1/C7H6ClNO2/c1-11-6-3-2-5(4-10)7(8)9-6/h2-4H,1H3
95652-80-5Relevant articles and documents
Transformations of trichloromethyl groups during reactions of 3-trichloromethylpyridines with methoxide
Dainter, Ronald S.,Jackson, Tracey,Omar, Abdirahman H. H.,Suschitzky, Hans,Wakefield, Basil J.,Hughes, Nigel,Nelson, Anthony J.,Varvounis, George
, p. 283 - 287 (2007/10/02)
When methoxide ion attacks an unsubstituted 2- or 6-position of a 3-trichloromethylpyridine, a hydrogen shift leads to a methoxy-substituted 3-dichloromethylpyridine. Further reaction of the dichloromethyl group with methoxide gives the corresponding acetal. This type of reaction has been applied to several chlorinated 3-trichloromethylpyridines and to 3- trichloromethylpyridine itself; a convenient synthesis of the latter is described.
