957208-65-0

Basic information

• Product Name: 4-ChloroMethyl-1-cyclopentyl-2-trifluoroMethyl-benzene
• Synonyms: 4-ChloroMethyl-1-cyclopentyl-2-trifluoroMethyl-benzene;4-CHLOROMETHYL-1-CYCLOPENTYL-2-TRIFLUOROMETHYL-BENZENE(WXG02030)
• CAS NO: 957208-65-0
• Molecular Formula: C₁₃H₁₄ClF₃
• Molecular Weight: 262.6984696
• Mol File: 957208-65-0.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 293.7±35.0 °C(Predicted)
• Appearance: /
• Density: 1.226±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 4-ChloroMethyl-1-cyclopentyl-2-trifluoroMethyl-benzene(CAS DataBase Reference)
• NIST Chemistry Reference: 4-ChloroMethyl-1-cyclopentyl-2-trifluoroMethyl-benzene(957208-65-0)
• EPA Substance Registry System: 4-ChloroMethyl-1-cyclopentyl-2-trifluoroMethyl-benzene(957208-65-0)

Safety Data

• Hazardous Substances Data: 957208-65-0(Hazardous Substances Data)

Usage

General Description

4-ChloroMethyl-1-cyclopentyl-2-trifluoroMethyl-benzene is a chemical compound that is composed of a benzene ring with a chloromethyl group, a cyclopentyl group, and a trifluoromethyl group attached at different positions on the ring. 4-ChloroMethyl-1-cyclopentyl-2-trifluoroMethyl-benzene is used in the synthesis of various pharmaceuticals and agrochemicals due to its unique structure and properties. It is also used as a building block in organic synthesis and research. However, it is important to handle this compound with caution as it may be hazardous if not used properly.

Upstream product

• 1206125-13-4 1-(2-(trifluoromethyl)phenyl)cyclopentanol 
• 392-83-6 o-trifluoromethylphenyl bromide 
• 956904-10-2 4-trifluoromethanesulfonyloxy-3-trifluoromethylbenzoic acid methyl ester 
• 110-88-3 1,3,5-Trioxan 
• 1206125-14-5 1-cyclopentyl-2-(trifluoromethyl)benzene 
• 115933-50-1 methyl 4-hydroxy-3-(trifluoromethyl)benzoate 
• 120-92-3 cyclopentanone 
• 220239-68-9 4-hydroxy-3-(trifluoromethyl)benzoic acid 
• 1737-36-6 4-chloro-3-(trifluoromethyl)benzoic acid 
• 161622-16-8 methyl 4-cyclopentyl-3-(trifluoromethyl)benzoate 
• 1206125-18-9 4-cyclopentyl-3-(trifluoromethyl)benzaldehyde 
• 1206125-16-7 4-bromo-1-cyclopentyl-2-(trifluoromethyl)benzene 
• 115591-64-5 4-chloro-3-trifluoromethylbenzoic acid methyl ester 
• 957205-39-9 (4-cyclopentyl-3-(trifluoromethyl)phenyl)methanol 

Downstream Products

• 1206125-27-0 1-cyclopentyl-4-((4-nitrophenoxy)methyl)-2-(trifluoromethyl)benzene 
• 1206124-34-6 (R/S)-ethyl 2-(7-(4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetate 
• 1206123-37-6 [(3R)-7-{[4-cyclopentyl-3-(trifluoromethyl)phenyl]methoxy}-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl]acetic acid 
• 1206123-97-8 (R)-2-(7-(4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetic acid, L-arginine salt 
• 1206123-55-8 2-(7-(4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetic acid 
• 1215119-22-4 ethyl 2-(2-(4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-6,7,8,9-tetrahydropyrido[1,2-a]indol-9-yl)acetate 
• 1215118-70-9 tert-butyl 2-(7-(4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-2,3-dihydro-1H-pyrrolo[1,2-a]indol-1-yl)acetate 

Relevant articles and documents

AROMATIC RING DERIVATIVE AS IMMUNOREGULATION AND PREPARATION METHOD AND APPLICATION OF AROMATIC RING DERIVATIVE

Relating to a compound represented by formula (I) and a pharmaceutically acceptable salt of the compound, and an application of the compound as an S1P1 agonist.

An Efficient Scale-Up Process for the Preparation of the APD334 Precursor 4-Chloromethyl-1-cyclopentyl-2-(trifluoromethyl)benzene

Synthetic studies of the APD334 precursor 4-chloromethyl-1-cyclopentyl-2-(trifluoromethyl)benzene (6) are described. A two-step scalable process was developed starting from commercially available and inexpensive starting materials. An iron(III) chloride-c

PROCESSES FOR THE PREPARATION OF (R)-2-(7-(4-CYCLOPENTYL-3-(TRIFLUOROMETHYL)BENZYLOXY)-1,2,3,4-TETRAHYDROCYCLOPENTA[B]INDOL-3-YL)ACETIC ACID AND SALTS THEREOF

The present invention relates to processes and intermediates useful in the preparation of of (R)-2-(7-(4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetic acid of Formula (Ia) and salts thereof, an S1P1 receptor modulator that is useful in the treatment of S1P1 receptor-associated disorders, for example, diseases and disorders mediated by lymphocytes, transplant rejection, autoimmune diseases and disorders, inflammatory diseases and disorders (e.g., acute and chronic inflammatory conditions), cancer, and conditions characterized by an underlying defect in vascular integrity or that are associated with angiogenesis such as may be pathologic (e.g., as may occur in inflammation, tumor development and atherosclerosis).