957785-24-9Relevant articles and documents
Total synthesis of streptonigrone
Chan, Bryan K.,Ciufolini, Marco A.
, p. 8489 - 8495 (2008/02/13)
(Chemical Equation Presented) A total synthesis of streptonigrone, 1, is described, which incorporates a one-step synthesis of substituted pyridones devised in our laboratory. Other aspects of the synthesis that differentiate the present approach from previous ones are the use of a Conrad-Limpach reaction, rather than the customary Friedlaender methodology, to assemble the quinoline segment of 1, and the implementation of an anionic sequence for the functionalization of a key pyridone intermediate.