95924-70-2

Upstream product

• 2026-48-4 (S)-valinol 
• 1148-11-4 N-Benzyloxycarbonyl-L-proline 
• 543-27-1 isobutyl chloroformate 
• 3397-33-9 Z-proline N-hydroxysuccinimide ester 
• 72-18-4 L-valine 
• 4276-09-9 (R)-2-amino-3-methylbutanol 
• 61350-60-5 (S)-benzyloxycarbonyl-proline acid chloride 

Downstream Products

• 109522-76-1 2-<<<3,3-Difluoro-2-hydroxy-1-(1-methylethyl)-4-oxo-4-<(2-phenylethyl)amino>butyl>amino>carbonyl>-1-pyrrolidinecarboxylic acid phenylmethyl ester 
• 119720-81-9 (S)-N-Acetyl-L-alanyl-N-<3,3-difluoro-1-(1-methylethyl)-2,4-dioxo-4-<(2-phenylethyl)amino>butyl>-L-prolinamide 
• 119720-82-0 N-Acetyl-L-alanyl-N-<3,3-difluoro-2-hydroxy-1-(1-methylethyl)-4-oxo-4-<(2-phenylethyl)amino>butyl>-L-prolinamide 
• 109522-75-0 2-<<<3,3-Difluoro-2-hydroxy-1-(1-methylethyl)-4-(ethoxy-4-oxobutyl)>amino>carbonyl>-1-pyrrolidinecarboxylic acid phenylmethyl ester 
• 109522-83-0 N-<3,3-Difluoro-2-hydroxy-1-(1-methylethyl)-4-oxo-4-<(2-phenylethyl)amino>butyl>-2-pyrrolidinecarboxamide 
• 700875-91-8 (2S)-2-{(4S)-4-isopropyl-4,5-dihydro-1,3-oxazol-2-yl}pyrrolidine-1-carboxylic acid benzyl ester 
• 109522-66-9 *,R^*)>-2-<<<1-Formyl-2-methylpropyl>amino>carbonyl>-1-pyrrolidinecarboxylic acid phenylmethyl ester 

Relevant academic research and scientific papers

Synthesis and characterization of new chiral azolinium salts, precursors to N-heterocyclic carbenes, derived from l-proline

A short and flexible procedure for the preparation of seven chiral azolinium and five functionalized chiral azolinium salts, precursors to N-heterocyclic carbenes, derived from l-proline has been developed. Moderate to good overall yields were obtained. Some NHC dimers and thiones were isolated. X-ray crystal structure determinations of two [Rh-NHC] complexes were also reported.

Distinctive meta-directing group effect for iridium-catalyzed 1,1-diarylalkene enantioselective hydrogenation

An iridium-catalyzed asymmetric hydrogenation of 1,1-diarylkenes is described. Employing a novel, modular phosphoramidite ligand, PhosPrOx, in this transformation affords biologically relevant 1,1-diarylmethine products in good enantiomeric ratios (96.5:3

Preparation of pyrrolidine-oxazoline containing ligands and their application in asymmetric transfer hydrogenation

Nine members of a new ligand class incorporating both an oxazoline ring and a pyrrolidine unit were prepared in an efficient four-step synthesis starting from readily available chiral amino alcohols and proline. A study of these ligands in the asymmetric transfer hydrogenation of acetophenone showed that the catalysts formed from [Ir(cod)Cl]2 were the most active while those derived from [Ru(p-cymene)Cl2]2 gave the highest enantioselectivities (up to 61% ee).

Fungal metabolites. XVIII. new membrane-modifying peptides, trichorozins I-IV, from the fungus Trichoderma harzianum

New membrane-modifying peptides, trichorozins I-IV, have been isolated from conidia of the fungus Trichoderma harzianum. Their amino acid sequences were clearly determined by spectrometric methods and, furthermore, they were synthesized by the solution-ph

Crystal structure of the covalent complex formed by a peptidyl α,α-difluoro-β-keto amide with porcine pancreatic elastase at 1.78-A resolution

The crystal structure analysis of the covalent enzyme-inhibitor complex of porcine pancreatic elastase (PPE) with a peptidyl α,α-difluoro-β-keto amide has shown that the tightly bound inhibitor forms an hemiketal complex with the O(γ) atom of the catalyti

Aralkylcarbamoyl peptide alcohols

Aralkylcarbamoyl peptide alcohols of the formula STR1 selectively stimulate nitrate and ammonium ion uptake by plants.