96014-55-0

Basic information

• Product Name: (S)-METHYL 4-(BOC-AMINO)-5-TBDMS-PENTANOATE
• Synonyms: (S)-METHYL 4-(BOC-AMINO)-5-TBDMS-PENTANOATE;(S)-METHYL 4-(TERT-BUTOXYCARBONYLAMINO)-5-(TERT-BUTYLDIMETHYLSILYLOXY) PENTANOATE;(S)-4-[[(tert-Butoxy)carbonyl]amino]-5-[[(tert-butyl)dimethylsilyl]oxy]pentanoic acid methyl ester
• CAS NO: 96014-55-0
• Molecular Formula: C₁₇H₃₅NO₅Si
• Molecular Weight: 361.55
• Mol File: 96014-55-0.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 408.1 °C at 760 mmHg
• Flash Point: 200.6 °C
• Appearance: /
• Density: 0.983
• Refractive Index: 1.447
• CAS DataBase Reference: (S)-METHYL 4-(BOC-AMINO)-5-TBDMS-PENTANOATE(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-METHYL 4-(BOC-AMINO)-5-TBDMS-PENTANOATE(96014-55-0)
• EPA Substance Registry System: (S)-METHYL 4-(BOC-AMINO)-5-TBDMS-PENTANOATE(96014-55-0)

Safety Data

• Hazardous Substances Data: 96014-55-0(Hazardous Substances Data)

Usage

General Description

(S)-Methyl 4-(BOC-amino)-5-TBDMS-pentanoate is a chemical compound with the molecular formula C17H31NO4Si. It is a derivative of pentanoic acid, and it contains a tert-butyloxycarbonyl (BOC) protecting group on the amino function, as well as a tert-butyldimethylsilyl (TBDMS) protecting group on the hydroxyl function. (S)-METHYL 4-(BOC-AMINO)-5-TBDMS-PENTANOATE is commonly used in organic synthesis and medicinal chemistry as a building block for the synthesis of various pharmaceuticals and bioactive compounds. It is also useful in the preparation of peptide and amide derivatives. Additionally, (S)-Methyl 4-(BOC-amino)-5-TBDMS-pentanoate is known for its ability to act as a chiral building block, making it valuable in the production of enantiomerically pure compounds for drug development and other applications.

InChI:InChI=1/C17H35NO5Si/c1-16(2,3)23-15(20)18-13(10-11-14(19)21-7)12-22-24(8,9)17(4,5)6/h13H,10-12H2,1-9H3,(H,18,20)/t13-/m0/s1

Upstream product

• 81658-26-6 tert-butyl (S)-2-(((tert-butyldimethylsilyl)oxy)methyl)-5-oxopyrrolidin-1-carboxylate 
• 39538-20-0 (S)-2-tert-Butoxycarbonylamino-pentanedioic acid 1-(2,5-dioxo-pyrrolidin-1-yl) ester 5-methyl ester 
• 45214-91-3 (2S)-2-[(tert-butoxy)carbonylamino]-4-(methoxycarbonyl)butanoic acid 
• 24424-99-5 di-tert-butyl dicarbonate 
• 1499-55-4 L-glutamic acid 5-methyl ester 
• 126587-35-7 methyl (4S)-4-[(tert-butoxy)carbonylamino]-5-hydroxypentanoate 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 34619-03-9 tert-butyldicarbonate 

Downstream Products

• 106191-02-0 (S)-5-((tert-butyldimethylsilyloxy)methyl)pyrrolidin-2-one 
• 81658-26-6 tert-butyl (S)-2-(((tert-butyldimethylsilyl)oxy)methyl)-5-oxopyrrolidin-1-carboxylate 
• 81658-27-7 (S)-tert-butyl 2-(((tert-butyldimethylsilyl)oxy)methyl)-5-oxo-2,5-dihydro-1H-pyrrole-1-carboxylate 
• 293297-95-7 (5S)-N-(tert-Butoxycarbonyl)-5-(((tert-butyldimethylsilyl)oxy)methyl)-3-(phenylseleno)pyrrolidin-2-one 
• 220623-07-4 (1S,2S,5R)-tert-butyl 3-aza-4-oxo-2-<(1,1,2,2-tetramethyl-1-silapropoxy)methyl>bicyclo<3.1.0>hexane-3-carboxylate 
• 96014-23-2 (S)-4-amino-4,5-dihydro-2-furancarboxylic acid 
• 96093-49-1 4-Amino-4,5-dihydro-furan-2-carboxylic acid 
• 1422740-23-5 C₂₈H₃₆N₂O₅ 
• 1422740-24-6 C₃₂H₃₈N₂O₅ 
• 1276112-33-4 C₃₂H₃₉NO₆ 
• 1276112-41-4 C₃₅H₄₃NO₅ 
• 1276112-34-5 C₃₅H₄₃NO₅ 
• 126587-35-7 methyl (4S)-4-[(tert-butoxy)carbonylamino]-5-hydroxypentanoate 
• 1422740-11-1 C₃₃H₅₁NO₆Si 

Relevant articles and documents

New approach toward the total synthesis of (+)-batzellaside B

A new synthetic approach to (+)-batzellaside B from naturally abundant L-pyroglutamic acid is presented in this article. The key synthetic step involves Sharpless asymmetric dihydroxylation of an olefinic substrate functionalized with an acetoxy group to

NEW ROUTES TO THE SYNTHESES OF CIS-α-(CARBOXYCYCLOPROPYL)GLYCINES FROM L-GLUTAMIC ACID. CONFORMATIONALLY RESTRICTED ANALOGUES OF THE EXCITATORY NEUROTRANSMITTER L-GLUTAMIC ACID

Potent neuroactive amino acids, (2S,2S,4R) and (2S,3R,4S) isomers of α-(carboxycyclopropyl)glycines (CCG-III and CCG-IV), were synthesized from L-glutamic acid via a palladium(II) catalyzed cyclopropanation of the α,β-unsaturated pyrrolidone and γ-amino-δ-lactone derivatives, respectively.