960589-86-0

Upstream product

• 75-77-4 chloro-trimethyl-silane 
• 17407-55-5 (S)-2-Hydroxy-3-methylbutanoic acid 
• 999-97-3 1,1,1,3,3,3-hexamethyl-disilazane 

Downstream Products

• 65138-05-8 (S)-2-hydroxy-3-methylbutyric acid benzyl ester 
• 872689-53-7 (S)-2-(tert-Butoxycarbonyl-methyl-amino)-3-hydroxy-3-methyl-butyric acid (R)-1-benzyloxycarbonyl-2-methyl-propyl ester 
• 872689-55-9 (S)-2-tert-Butoxycarbonylamino-3-hydroxy-3-methyl-butyric acid (R)-1-benzyloxycarbonyl-2-methyl-propyl ester 
• 872689-54-8 (S)-N-butoxycarbonyl-N-methylvaline (1R)-2-methyl-1-[(phenylmethoxy)carbonyl]propyl ester 

Relevant academic research and scientific papers

Synthesis of a substituted benzazepin-2-one dihydrate

Synthesis of the title compound was accomplished via coupling of (S)-alaninyl-(S)-1-amino-3-methyl-4,5,6,7-tetrahydro-2H-3-benzazepin-2-one with the activated trimethylsilyl ester of (S)-2-trimethylsilyloxy-3-methylbutyric acid, followed by deprotection a

Synthesis and application of L-N-Boc-N-methyl-β-hydroxyvaline in the preparation of a depsipeptide

Enantiopure (>99% ee) L-N-tert-butyloxycarbonyl-N-methyl-β- hydroxyvaline (2) was synthesized in six steps and 43% overall yield from D-serine methyl ester (5). Methyl (4S)-N-(9-phenylfluoren-9-yl)-oxazolidine-4- carboxylate (7) was prepared in two steps