962-25-4

Basic information

• Product Name: 2-(4-Chlorophenyl)-5-nitrobenzoxazole
• Synonyms: 2-(4-Chlorophenyl)-5-nitrobenzoxazole;5-Nitro-2-[4-chlorophenyl]benzoxazole
• CAS NO: 962-25-4
• Molecular Formula: C₁₃H₇ClN₂O₃
• Molecular Weight: 274.65928
• Mol File: 962-25-4.mol
• Article Data: 13

Chemical Properties

• Melting Point: 218-219 °C
• Boiling Point: 403.4±25.0 °C(Predicted)
• Appearance: /
• Density: 1.455±0.06 g/cm3(Predicted)
• PKA: -5.97±0.10(Predicted)
• CAS DataBase Reference: 2-(4-Chlorophenyl)-5-nitrobenzoxazole(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-Chlorophenyl)-5-nitrobenzoxazole(962-25-4)
• EPA Substance Registry System: 2-(4-Chlorophenyl)-5-nitrobenzoxazole(962-25-4)

Safety Data

• Hazardous Substances Data: 962-25-4(Hazardous Substances Data)

Upstream product

• 104-88-1 4-chlorobenzaldehyde 
• 99-57-0 2-hydroxy-5-nitroaniline 
• 369-36-8 6-fluoro-3-nitroaniline 
• 122-01-0 4-chloro-benzoyl chloride 
• 83392-36-3 methyl 3-(4-chlorophenyl)-3-oxopropanedithioate 
• 70886-33-8 5-nitro-benzooxazole 
• 873-76-7 para-Chlorobenzyl alcohol 
• 10403-47-1 2-bromo 5-nitroaniline 

Relevant articles and documents

A TEMPO-Functionalized Ordered Mesoporous Polymer as a Highly Active and Reusable Organocatalyst

The properties of high stability, periodic porosity, and tunable nature of ordered mesoporous polymers make these materials ideal catalytic nanoreactors. However, their application in organocatalysis has been rarely explored. We report herein for the first time the incorporation of a versatile organocatalyst, 2,2,6,6-tetramethyl-1-piperidinyloxy (TEMPO), into the pores of an FDU-type mesoporous polymer via a pore surface engineering strategy. The resulting FDU-15-TEMPO possesses a highly ordered mesoporous organic framework and enhanced stability, and shows excellent catalytic activity in the selective oxidation of alcohols and aerobic oxidative synthesis of 2-substituted benzoxazoles, benzimidazoles and benzothiazoles. Moreover, the catalyst can be easily recovered and reused for up to 7 consecutive cycles.

Organocatalytic oxidative synthesis of C2-functionalized benzoxazoles, naphthoxazoles, benzothiazoles and benzimidazoles

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Deep eutectic solvent-catalyzed arylation of benzoxazoles with aromatic aldehydes

A novel and efficient methodology for the arylation of benzoxazoles with aromatic aldehydes catalyzed by deep eutectic solvent has been developed. The reaction smoothly proceeded with a wide range of substrates to give the desired products in high yields within short reaction time. Deep eutectic solvents are easily recovered and reused without significant loss of catalytic activity.