96294-85-8

Basic information

• Product Name: 4-methyl-1-(propan-2-yl)-2-(propan-2-yloxy)benzene
• CAS NO: 96294-85-8
• Molecular Formula: C₁₃H₂₀O
• Molecular Weight: 192.2973
• Mol File: 96294-85-8.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 265.9°C at 760 mmHg
• Flash Point: 95.1°C
• Density: 0.902g/cm³
• Vapor Pressure: 0.0147mmHg at 25°C
• Refractive Index: 1.485
• CAS DataBase Reference: 4-methyl-1-(propan-2-yl)-2-(propan-2-yloxy)benzene(CAS DataBase Reference)
• NIST Chemistry Reference: 4-methyl-1-(propan-2-yl)-2-(propan-2-yloxy)benzene(96294-85-8)
• EPA Substance Registry System: 4-methyl-1-(propan-2-yl)-2-(propan-2-yloxy)benzene(96294-85-8)

Safety Data

• Hazardous Substances Data: 96294-85-8(Hazardous Substances Data)

Upstream product

• 75-29-6 isopropyl chloride 
• 37693-11-1 sodium 5-methyl-2-(1-methylethyl)phenolate 
• 75-26-3 isopropyl bromide 
• 19177-04-9 1-isopropoxy-3-methylbenzene 
• 7637-07-2 boron trifluoride 
• 86119-84-8 phosphoric acid 
• 75-30-9 2-iodo-propane 
• 89-83-8 thymol 
• 108-39-4 3-methyl-phenol 
• 67-63-0 isopropyl alcohol 

Downstream Products

• 40625-96-5 5-methyl-2,4-diisopropylphenol 

Relevant articles and documents

COMPOSITIONS AND METHODS FOR IMMUNE MODULATION AND TREATMENT OF CANCER

The disclosure relates to rexinoids, including compounds of the Formula (I) and (II) or a pharmaceutically acceptable salt, polymorph, prodrug, solvate or clathrate thereof. These rexinoids are useful for increasing PD-L1 in vivo, for treatment of cancer, and for inhibiting the onset of cancer.

Isopropylation of m-cresol over mesoporous Al-MCM-41 molecular sieves

A study on the isopropylation of m-cresol with isopropyl alcohol was carried out utilizing Al-MCM-41 molecular sieves with Si/Al ratios of 59:1, 103:1, and 202:1 at 250°-400°C. The products obtained were 2-isopropyl-5-methylphenol (IMP), isopropyl-3-methylphenyl ether (IMPE), and isopropyl-(2-isopropyl-5-methylphenyl) ether (IIMPE). The m-cresol conversion increased till 300°C, after which it decreased. The selectivity of 2-isopropyl-5-methylphenol (IMP) was more than that of the other products. Of the three catalysts studied for isopropylation of m-cresol with isopropyl alcohol in the vapor phase, AI-MCM-41 (59) was more suitable than Al-MCM-41 (103) and Al-MCM-41 (202). The feed ratio of 1:2 was more suitable for better conversion and 100% selectivity to IMP. The study of time on stream indicates the retention of activity even after 10 hr with the feed ratio of 1:4 for nearly 10% conversion. Al-MCM-41 could be a convenient and ecofriendly alternative to the hazardous and highly corrosive mineral acid catalysts for m-cresol isopropylation.