96495-22-6Relevant articles and documents
17a-HYDROXYLASE/C17,20-LYASE INHIBITORS
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Paragraph 1178, (2014/03/21)
The present invention provides compounds of Formula (I), or a pharmaceutically acceptable salt thereof, where R1, R2, R3, R4, R5, R6, A and n are as defined herein. A deuteriated derivative of the compound of Formula (I) is also provided.
17α-HYDROXYLASE/C17,20-LYASE INHIBITORS
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Page/Page column 192, (2012/04/04)
The present invention provides compounds of Formula (I), or a pharmaceutically acceptable salt thereof, where R1, R2, R3, R4, R5, R6, A and n are as defined herein. A deuteriated derivative of the compound of Formula (I) is also provided.
Synthesis and Pharmacological Characteization of 2-(4-Chloro-3-hydroxyphenyl)ethylamine and N,N-Dialkyl Derivatives as Dopamine Receptor Ligands
Claudi, Francesco,Giorgioni, Gianfabio,Stefano, Antonio Di,Abbracchio, Maria Pia,Paoletti, Anna Maria,et al.
, p. 4408 - 4414 (2007/10/02)
2-(4-chloro-3-hydroxyphenyl)ethylamine (4) and some derivatives were synthesized as dopamine (DA) receptor ligands.Amine 4 retains the dopaminergic pharmacophore 2-(3-hydroxyphenyl)ethylamine, and the chlorine atom replaces the "para" hydroxyl group of DA