96720-09-1Relevant articles and documents
Homoallylic Chiral Induction in the Synthesis of 2,4-Disubstituted Tetrahydrofurans by Iodoetherification. Synthetic Scope and Chiral Induction Mechanism
Labelle, M.,Morton, H. E.,Guindon, Y.,Springer, J. P.
, p. 4533 - 4540 (2007/10/02)
Chiral induction generating two new stereogenic centers has been observed in the iodoetherification of optically active ethyl 5,6-dihydroxyhexenoate.Of the pour possible isomeric tetrahydrofuran products, only two were obtained in rations up to 12:1 favor
PREPARATION OF ETHYL 5(S),6-EPOXY-3(R)-(METHOXYMETHOXY)HEXANOATE: A KEY CHIRAL INTERMEDIATE FOR MEVINOLIN AND COMPACTIN.
Guindon, Yvan,Yoakim, Christiane,Bernstein, Michael A.,Morton, Howard E.
, p. 1185 - 1188 (2007/10/02)
The synthesis of Ethyl 5(S),6-Epoxy-3(R)-(methoxymethoxy)hexanoate, a key chiral synthon for the β-hydroxy-δ-lactone portion of Mevinolin and Compactin, via a regiospecific ring opening of a tetrahydrofuran derivative by dimethyboron bromide, is described.