96720-12-6Relevant articles and documents
PREPARATION OF ETHYL 5(S),6-EPOXY-3(R)-(METHOXYMETHOXY)HEXANOATE: A KEY CHIRAL INTERMEDIATE FOR MEVINOLIN AND COMPACTIN.
Guindon, Yvan,Yoakim, Christiane,Bernstein, Michael A.,Morton, Howard E.
, p. 1185 - 1188 (2007/10/02)
The synthesis of Ethyl 5(S),6-Epoxy-3(R)-(methoxymethoxy)hexanoate, a key chiral synthon for the β-hydroxy-δ-lactone portion of Mevinolin and Compactin, via a regiospecific ring opening of a tetrahydrofuran derivative by dimethyboron bromide, is described.